Samoylenko et al., Cell Signal 2008
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Using phospho-kinase arrays and Western blot we found downregulation of the NGF stimulated phosphorylation of the extracellular signal regulated kinase p42ERK by TPO with no effect on phosphorylation of Akt or stress kinases
Virdee et al., J Neurochem 1996
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Nerve growth factor (NGF) induces persistent p42 and p44 mitogen activated protein kinase ( MAPK ) activity in sympathetic neurones in parallel to its survival promoting activity
Klinz et al., J Neurosci Res 1996
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At this concentration NGF stimulated tyrosine phosphorylation of MAP kinase p42 as well as MAP kinase activity both were decreased by approximately 80 %