Gene interactions and pathways from curated databases and text-mining

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INS — NIDDM1

Text-mined interactions from Literome

Kristensen et al., Ugeskr Laeger 1999 (Diabetes Mellitus, Type 1...) : One hundred an fourty ( 1.8 % ) of the patients had recognized diabetes and 81 % of these diabetes had non-insulin dependent diabetes ( NIDDM )
Johnsen et al., Ugeskr Laeger 1999 (Diabetes Mellitus, Type 2...) : The purpose of this study was to evaluate Mg status by nuclear magnetic resonance spectroscopy in a group of well regulated non-insulin dependent diabetic ( NIDDM ) patients without angiopathy
Ireland et al., Pharm Pract Manag Q 1997 (Diabetes Mellitus, Type 2) : This frequency has been estimated at 30 to 50 percent, although because of underdiagnosis, reported cases have approximately a 20 percent occurrence, the majority of which is Type II or non-insulin dependent diabetes ( NIDDM )
Muller et al., J Insur Med 1998 (Diabetes Mellitus, Type 1...) : Non insulin dependent diabetic ( NIDDM ) mortality is 1.4 to 3.7 times that of non-diabetics
Nuttall et al., QJM : monthly journal of the Association of Physicians 1999 (Diabetes Mellitus, Type 2) : Impaired antioxidant defence is implicated in the development of cardiovascular complications in non-insulin dependent diabetes ( NIDDM )
Hattersley et al., Lancet 1999 (Cardiovascular Diseases...) : Low birthweight is associated with insulin resistance, hypertension, coronary-artery disease, and non-insulin dependent diabetes ( NIDDM )
Tomino et al., Nephron 1999 (Diabetes Mellitus, Type 2...) : We determined the relationship between the gene polymorphism of angiotensinogen (AGT), angiotensin converting enzyme (ACE), or angiotensin II receptor ( AT1R ) and the progression of diabetic nephropathy in a multicenter trial of ethnically homogeneous Japanese patients with non-insulin dependent diabetes ( NIDDM )
Vergès et al., Diabetes Metab 1999 (Arteriosclerosis...) : Both types are present in non-insulin dependent diabetes ( NIDDM ) and poorly controlled insulin dependent diabetes ( IDDM ), whereas only qualitative abnormalities are observed in well- and moderately well controlled IDDM
Morris et al., J Trace Elem Med Biol 1999 (Diabetes Mellitus, Type 2) : The purpose of this study was to assess chromium handling in non-insulin dependent diabetic patients ( NIDDM ) compared to healthy volunteers
Nicholson et al., Prev Med 1999 (Body Weight...) : To investigate whether glycemic and lipid control in patients with non-insulin dependent diabetes ( NIDDM ) can be significantly improved using a low-fat, vegetarian ( vegan ) diet in the absence of recommendations regarding exercise or other lifestyle changes
Stilling et al., Nutr Metab Cardiovasc Dis 1999 (Diabetes Mellitus, Type 2) : The aim of the study was to evaluate the effect on blood glucose levels in non-insulin dependent diabetics ( NIDDM ) of reduction of the carbohydrate content through the use of a new, almost starch-free type of bread ( SF-bread )
Sugimoto et al., Clin Exp Pharmacol Physiol 1999 (Body Weight...) : 1. The influence of angiotensin converting enzyme (ACE) inhibitor is investigated in enalapril on renal function in Otsuka Long-Evans Tokushima Fatty ( OLETF ) rats, an animal model of spontaneously non-insulin dependent diabetes ( NIDDM )
Mori et al., Metabolism 1999 (Diabetes Mellitus, Type 2...) : We therefore aimed to assess the independent and combined effects of dietary omega3 fatty acids and aerobic exercise training on urinary F2-isoprostane levels in dyslipidemic non-insulin dependent diabetic ( NIDDM ) patients
Rauramaa et al., Med Sci Sports Exerc 1999 (Obesity) : Obesity is a risk factor for atherosclerotic cardiovascular diseases, and it is associated with hypertriglyceridemia, hyperinsulinemia, and non-insulin dependent diabetes ( NIDDM )
Klein et al., J Endocrinol 2000 (Diabetes Mellitus, Type 2...) : To examine whether such an effect of glucose can also be demonstrated in vivo, insulin receptor kinase activation was studied in erythrocytes from 11 patients with non-insulin dependent diabetes ( NIDDM ), before and after reduction of hyperglycemia ( from 14.6+/-1.6 to 6.6+/-0.5 mmol/l fasting plasma glucose within 8.6+/-0.6 days ) ... We conclude that insulin activation of erythrocyte insulin receptor kinase is not impaired in NIDDM and is not influenced by hyperglycemia
Christensen et al., Scand J Clin Lab Invest 2000 (Albuminuria...) : Patients with non-insulin dependent diabetes ( NIDDM ) are at independent risk of cardiovascular death
Manzella et al., J Clin Endocrinol Metab 2001 (Diabetes Mellitus, Type 2) : Thus, we investigated the effect of changes in plasma FFA levels on HRV, in non-insulin dependent diabetes ( NIDDM ) patients
Papadakis et al., J Diabetes Complications 2001 (Diabetes Mellitus, Type 2...) : Patients with non-insulin dependent diabetes ( NIDDM ) have an increased incidence of ischaemic heart disease ( IHD ) when compared with nondiabetic subjects
Kechrid et al., Diabetes Metab 2001 (Diabetes Mellitus, Type 2...) : To investigate the effect of low-Zn diet on ( 65 ) Zn turnover and content in non-insulin dependent diabetes ( NIDDM )
Murali et al., Pharmacol Res 2001 (Diabetes Mellitus, Experimental...) : Improvement in insulin sensitivity by losartan in non-insulin dependent diabetic ( NIDDM ) rats
Lin et al., Diabetes 2001 (Diabetes Mellitus, Type 2...) : When glucose was raised to 11 mmol/l, insulin release increased significantly in Niddm1f and F344 islets but was essentially unchanged in islets from GK and Niddm1i
Janghorbani et al., Ophthalmic Epidemiol 2001 (Diabetes Mellitus, Type 1...) : Using a Cox 's Proportional Hazards Model for insulin dependent diabetes ( IDDM ) and NIDDM ( insulin and non-insulin treated ) diabetes separately, longer duration of diabetes, higher systolic blood pressure and poor metabolic control were significant independent predictors of retinopathy for all three groups
Murali et al., J Ethnopharmacol 2002 (Diabetes Mellitus, Type 2) : Effect of chronic treatment with Enicostemma littorale in non-insulin dependent diabetic ( NIDDM ) rats
Veening et al., J Clin Endocrinol Metab 2002 (Diabetes Mellitus, Type 2...) : NIDDM could result from a decreased insulin sensitivity or a reduced insulin secretion or a combination of both
Xu et al., Ren Fail 2002 (Albuminuria...) : That is, serum levels of type IV collagen in diabetic nephropathy were significantly higher than those found in non-insulin dependent diabetic ( NIDDM ) patients without nephropathy and in healthy subjects ( HS )
Deng et al., Hunan Yi Ke Da Xue Xue Bao 2001 (Diabetes Mellitus, Type 2) : To ascertain whether Gly40Ser mutation in exon 2 of glucagon receptor (GCG-R) gene is associated with late-onset non-insulin dependent diabetes millitus ( NIDDM ) in Chinese
Chang et al., Gaoxiong Yi Xue Ke Xue Za Zhi 1992 (Diabetes Mellitus...) : The purpose of this study was to determine the association of the prevalence of non-insulin dependent diabetes ( NIDDM ) with central obesity, obesity, and family history of diabetes
Alwan et al., World Health Stat Q 1992 (Diabetes Mellitus, Type 1...) : For non-insulin dependent diabetes ( NIDDM ) in adults, risk is higher in urban than in rural subjects, and in all populations prevalence increases with advancing age
Islas Andrade et al., Gaceta médica de México 1992 (Cadaver...) : The amount of neuroendocrine granules in microgranular cells of salivary glands were investigated in necropsies of 20 non-insulin dependent diabetics ( NIDDM ) and in 20 non-diabetic subjects with Grimelius and Fontana-Masson stainings
Akanji et al., Br J Nutr 1992 (Diabetes Mellitus, Type 2...) : In assessing the factors that determine TAG responses to acute fat loading in a tropical African population with a low prevalence of atherosclerotic disease, twenty ( nine obese ) non-insulin dependent diabetic ( NIDDM ) patients with optimal glycaemic control and twelve ( six obese ) age matched non-diabetic subjects were given meals containing 50 g fat ( in butter ) and 75 g carbohydrate ( in white bread ) over 15 min in the morning after a 12 h overnight fast
Robinson et al., Baillieres Clin Endocrinol Metab 1992 (Diabetes Mellitus...) : Non-insulin dependent diabetes ( NIDDM ), clinically similar to common NIDDM, may be found in some syndromes ( e.g. Werner 's syndrome )
Glassman et al., Spine J 2003 (Diabetes Mellitus, Type 1...) : To identify differences, if any exist, between patients with insulin dependent diabetes mellitus ( IDDM ) and non-insulin dependent diabetes ( NIDDM )
Sakura et al., J Clin Endocrinol Metab 1992 (Diabetes Mellitus, Type 2) : Then, by screening Japanese diabetic patients using polymerase chain reaction -- single strand conformation polymorphism ( PCR-SSCP ) and direct sequencing strategies, we identified a missense mutation substituting arginine ( AGG ) for glycine ( GGG ) at position 261 in exon 7 of the glucokinase gene in a patient with early-onset non-insulin dependent diabetes ( NIDDM )
Graber et al., Apoptosis 1999 : We have compared the concentrations of intracellular glutathione ( GSH ), glutathione dependent antioxidative enzymes, the cell death rate and immunophenotype profile of peripheral blood mononuclear cells ( PBMC ) from healthy donors and from patients with insulin dependent type II ( NIDDM ) diabetes mellitus
Kaneda et al., Acta Pathol Jpn 1992 (Diabetes Mellitus, Type 2...) : Mitochondrial enlargement and basement membrane thickening of renal proximal tubules, possible initiators of microalbuminuria in non-insulin dependent diabetics ( NIDDM )
Haneda et al., J Diabetes Complications 1992 (Albuminuria...) : In this study, 52 nonproteinuric Japanese patients with non-insulin dependent diabetes ( NIDDM ) were followed from 1985 to 1990 to investigate the rate of development and progression of microalbuminuria and the factors which influence it
Ramachandran et al., Ann Med 1992 (Diabetes Mellitus, Type 2) : Prevalence of non-insulin dependent diabetes ( NIDDM ) in India was reported to be 2.3 % in the urban and 1.5 % in the rural areas in the early 1970s by the Indian Council of Medical Research ( ICMR )
Gordon et al., Diabetes Care 1992 (Diabetes Mellitus, Type 1...) : GSP determinations from insulin dependent diabetic ( IDDM ) patients, non-insulin dependent diabetic ( NIDDM ) patients, and control subjects were correlated with other indices of glycemic control
Harris et al., Diabetes Care 1992 (Diabetes Mellitus, Type 2...) : Two population based groups of white patients with non-insulin dependent diabetes ( NIDDM ) in the United States and Australia were studied
Sosenko et al., Diabetes Care 1992 (Diabetes Mellitus, Type 2) : We studied whether sensory function abnormalities are present at diagnosis and whether they develop in the early stages of non-insulin dependent diabetes ( NIDDM )
Lee et al., Arch Pharm Res 2004 : Metformin is a biguanide antihyperglycemic agent often used for the treatment of non-insulin dependent diabetics ( NIDDM )
Tilly-Kiesi et al., J Lipid Res 1992 (Coronary Disease...) : The characteristics of low density lipoproteins (LDL) of ten non-insulin dependent diabetic ( NIDDM ) and ten nondiabetic patients with coronary artery disease ( CAD ) were investigated and compared to LDL of ten NIDDM patients without CAD and ten healthy persons
Bak et al., Am J Med 1992 (Diabetes Mellitus, Type 2...) : About 40 % of patients with non-insulin dependent diabetes ( NIDDM ) have hypertension, which in turn may contribute to their enhanced risk for cardiovascular diseases
Karam et al., Endocrinol Metab Clin North Am 1992 (Cerebrovascular Disorders...) : Non-insulin dependent diabetes ( NIDDM ) has long been recognized as being associated with a cluster of disorders including obesity, hypertension, dyslipidemia, and atherosclerotic heart disease
Zambon et al., Am J Clin Nutr 1992 (Diabetes Mellitus, Type 2) : Using a random crossover design, we examined the effects of glyburide for 4 wk on glucose, insulin, lipid, and lipoprotein metabolism in 10 men with non-insulin dependent diabetes ( NIDDM ) receiving dietary fish-oil concentrates containing omega 3 ( n-3 ) fatty acids ( 8 g/d )
Bochicchio et al., World J Surg 2006 (Critical Illness...) : Tobacco use ( 24 % ) was the most common risk factor identified, followed by hypertension ( HTN, 17 % ), coronary artery disease ( 9 % ), chronic obstructive pulmonary disease ( COPD ) /reactive airway disease ( 4 % ), non-insulin dependent diabetes ( NIDDM ) ( 4 % ), insulin dependent diabetes ( IDDM) (3.2 % ), cancer ( 3 % ), liver disease ( 2 % ), and HIV/AIDS ( 1.4 % )
Abbate et al., J Cardiovasc Pharmacol 1990 (Diabetes Mellitus...) : The non-insulin dependent diabetic ( NIDDM ) patient with mild fasting hyperglycemia commonly has mild hypertriglyceridemia due to overproduction of TG-rich lipoproteins in the liver, associated with decreased high-density lipoprotein ( HDL ) cholesterol levels
Mitrakou et al., N Engl J Med 1992 (Diabetes Mellitus, Type 2...) : Insulin resistance and impaired insulin secretion both occur in non-insulin dependent diabetes ( NIDDM ), but their relative importance is unclear
Al-Nuaim et al., Ann Saudi Med 1998 : Results : There were 613 confirmed non-insulin dependent diabetic patients ( NIDDM ), 50 % with good glycemic control
Das Evcimen et al., Pharmacol Res 2007 (Diabetic Angiopathies...) : There are two major types of diabetes mellitus : Type 1 diabetes ( insulin dependent diabetes, IDDM or juvenile onset diabetes ) and Type 2 diabetes ( non-insulin dependent diabetes, NIDDM or adult-onset )
Kocić et al., Vojnosanit Pregl 2007 (Diabetes Mellitus, Type 2...) : The study included 24 obese healthy and 16 obese newly diagnozed non-insulin dependent diabetic patients ( NIDDM ) as well as 20 control healthy subjects, matched in age
Chiba et al., J Diabet Complications 1991 (Albuminuria...) : This study was undertaken to examine whether patients with non-insulin dependent diabetes ( NIDDM ) are hypercalciuric and whether there is a pathophysiologic relationship between urinary calcium excretion ( UCE ) and the degree of diabetic nephropathy
Takahashi et al., J Diabet Complications 1991 (Diabetes Mellitus, Type 2...) : To clarify the characteristics of diabetic nephropathy (DN) in Japanese patients with non-insulin dependent diabetes ( NIDDM ), we analyzed the clinical course of 130 such patients who began dialysis treatment due to DN between 1978 and 1988 at the Diabetes Center of Tokyo Women 's Medical College
Katsumata et al., Diabetes Res Clin Pract 1991 (Diabetes Complications...) : All 13 diabetic patients had non-insulin dependent type diabetes ( NIDDM )
Cerasi et al., Diabetes Res Clin Pract 1991 (Diabetes Mellitus...) : The clinical and in vitro results plus literature data suggest that insulin resistance can be overcome by insulin in NIDDM, and that beta-cell responsiveness to glucose is greatly reduced in NIDDM , but the defect is restricted to the acute stimulatory phase of glucose induction of insulin release
Higgins et al., Acta Ophthalmol Scand 2007 (Diabetes Mellitus, Type 1...) : Of the 44 patients studied, 11 had type 1 diabetes mellitus ( DM ) and 33 had type 2 DM ( 11 insulin dependent DM [ IDDM ], 22 non-insulin dependent DM [ NIDDM ] )
Karlander et al., Diabetes Care 1991 (Diabetes Mellitus, Type 2) : To compare the long-term effect of combined treatment with insulin and glyburide versus insulin alone on serum lipid levels in non-insulin dependent diabetic ( NIDDM ) patients with secondary failure to sulfonylurea therapy
Viswanathan et al., Indian J Med Res 1991 (Albuminuria...) : Urinary albumin excretion ( UAE ) was estimated by radioimmunoassay in 316 non-insulin dependent diabetic patients ( NIDDM ), with diabetes for 10 or more years and proteinuria less than 150 mg/24 h. Albuminuria was determined in 24 h collection of urine in 259 patients but in the other 57, a random sample was used
Lim et al., Diabetes Res Clin Pract 1991 (Diabetes Mellitus, Type 1...) : There were 84 non-insulin dependent diabetics ( NIDDM ), prevalence 0.3 per 1000 inhabitants
Mykkänen et al., Atherosclerosis 1991 (Coronary Disease...) : Altogether 312 men and 515 women had normal glucose tolerance, 84 men and 158 women impaired glucose tolerance ( IGT ), 33 men and 59 women newly diagnosed non-insulin dependent diabetes ( NIDDM ) detected at the survey, and 82 men and 188 women previously diagnosed NIDDM
Gray et al., Am J Clin Nutr 1991 (Body Weight...) : In this study MRI was used to define fat-distribution patterns in 24 obese females with non-insulin dependent diabetes ( NIDDM ) and 12 females with simple obesity
Livingstone et al., Biochim Biophys Acta 1991 (Diabetes Mellitus, Type 2) : Altered G-protein expression and adenylate cyclase activity in platelets of non-insulin dependent diabetic ( NIDDM ) male subjects
Elkeles et al., Diabete Metab 1991 (Diabetes Mellitus, Type 2) : The effects of oral hypoglycaemic drugs on serum lipids and lipoproteins in non-insulin dependent diabetes ( NIDDM )
Fruchart et al., Diabete Metab 1991 (Arteriosclerosis...) : Non-insulin dependent diabetic patients ( NIDDM ) are characterized by increased concentrations of cholesteryl ester rich LpB and triglyceride rich LpB : C-III and LpB : E. ( ABSTRACT TRUNCATED AT 250 WORDS )
Ferriss et al., J Hum Hypertens 1991 (Diabetes Mellitus, Type 1...) : There is an increased prevalence of hypertension among patients with non-insulin dependent diabetes ( NIDDM )
Morgan et al., Diabetes 1990 (Diabetes Mellitus, Type 2...) : A cohort of 132 well documented White Welsh non-insulin dependent diabetic ( NIDDM ) subjects were genotyped for 5 restriction-fragment-length polymorphisms ( RFLPs ) at the insulin-receptor gene (IRG) locus and a polymorphic locus 5 ' to the insulin gene
Haffner et al., Am J Clin Nutr 1991 (Diabetes Mellitus, Type 2) : Many studies have shown an increased prevalence of non-insulin dependent diabetes ( NIDDM ) in individuals with an unfavorable body fat distribution, but there are still relatively few prospective studies on this topic
Shervais et al., Statistical applications in genetics and molecular biology 2010 (Diabetes Mellitus, Type 2...) : We applied RA to a real dataset of type 2 non-insulin dependent diabetes ( NIDDM ) cases and controls, and closely approximated the results of more conventional single SNP disease association studies
Gans et al., J Intern Med Suppl 1991 (Diabetes Mellitus, Type 2...) : Epidemiological evidence suggests that there is a close association between obesity, non-insulin dependent diabetes ( NIDDM ) and hypertension
Friedman et al., Diabetes Care 1991 (Diabetes Mellitus, Type 2...) : To evaluate, by means of a precise method, the rate of decline of glomerular filtration rate in proteinuric non-insulin dependent diabetic ( NIDDM ) patients
Ratheiser et al., Acta Diabetol Lat 1990 (Diabetes Mellitus, Type 2) : To determine quantitative and qualitative differences in insulin secretion equimolar amounts of glucose and arginine were infused in 9 healthy subjects, in 8 individuals each with obesity without and with impaired glucose tolerance, and in non-obese and obese non-insulin dependent diabetic patients ( NIDDM )
Uusitupa et al., Int J Clin Pharmacol Ther Toxicol 1990 (Body Weight...) : Nine patients with non-insulin dependent diabetes ( NIDDM ) treated with glibenclamide ( 3.5 mg b.i.d. ) participated in this randomized double-blind placebo controlled crossover study to evaluate the effects of granulated guar gum ( 5 g t.i.d. with meals ) on the absorption of glibenclamide and metabolic control and serum lipids
Liu et al., Scand J Prim Health Care 1990 (Body Weight...) : Twenty non-insulin dependent diabetic ( NIDDM ) patients with secondary failure to sulphonylureas were given combined insulin-glibenclamide therapy
Umpleby et al., Diabetes Res Clin Pract 1990 (Diabetes Mellitus, Type 2) : Glucose and leucine metabolism were investigated in 5 poorly controlled non-insulin dependent diabetics ( NIDDM ) following an i.v. injection of 3- [ 3H ] glucose and 1- [ 14C ] leucine in the morning and evening
Temple et al., Clin Endocrinol (Oxf) 1990 (Diabetes Mellitus...) : We have compared insulin concentrations measured by radioimmunoassay ( RIA ) in plasma from 50 fasting non-insulin dependent diabetics ( NIDDM ) with those measured by a new monoclonal antibody based two-site immunoradiometric assay ( IRMA ) of insulin ( which has no significant cross-reaction with proinsulin-like molecules )
Abbott et al., J Clin Invest 1990 (Diabetes Mellitus, Type 2) : In this study, kinetics of VLDL, intermediate density lipoprotein ( IDL ), and LDL apoprotein B and VLDL triglyceride were determined in seven nondiabetic ( ND ) and seven non-insulin dependent diabetic ( NIDDM ) Pima Indian subjects on high-fat and high-carbohydrate ( HICHO ) diets
Gregersen et al., Am J Clin Nutr 1990 (Diabetes Mellitus, Type 2) : The present study was carried out to see if either the volume of water or the duration of ingestion time influence the postprandial blood glucose and insulin responses in non-insulin dependent diabetic ( NIDDM ) subjects
Hendra et al., Diabetes Care 1990 (Cardiovascular Diseases...) : The aim of this study was to evaluate the effects of a fish oil preparation ( MaxEPA ) on hemostatic function and fasting lipid and glucose levels in non-insulin dependent diabetic ( NIDDM ) subjects
Snehalatha et al., J Assoc Physicians India 1990 (Diabetes Mellitus, Type 1...) : Immunoreactive insulin ( IRI ) and insulin degrading enzyme activity (IDEA) of the plasma and the corresponding erythrocyte lysate were estimated in 21 normal volunteers, 18 non insulin dependent diabetic patients ( NIDDM ), and 16 insulin dependent diabetics ( IDDM )
Cho et al., PloS one 2012 (Diabetes Mellitus, Type 2...) : Our findings suggest that the failure of the negative feedback regulation of CREB is the primary cause for ß-cell dysfunctions under conditions of pathogenic hyperglycemia, and PP2A can be a novel target for future therapies aiming to protect ß-cells mass in the late transitional phase of non-insulin dependent type 2 diabetes ( NIDDM )
Schmitz et al., J Intern Med 1990 (Albuminuria...) : Microalbuminuria in non-insulin dependent diabetes ( NIDDM ) is a strong predictor of increased mortality
Dallam et al., Health Promot Pract 2013 (Body Weight...) : The rapidly increasing rate of non-insulin dependent diabetes ( NIDDM ) among both market economy and developing countries is a worldwide health phenomenon
Laakso et al., Metabolism 1990 (Diabetes Complications...) : We studied the association of obesity with lipid and lipoprotein concentrations in 92 patients ( 49 men, 43 women ) with insulin dependent diabetes ( IDDM ), in 305 patients ( 152 men, 153 women ) with non-insulin dependent diabetes ( NIDDM ), and in 122 nondiabetic control subjects ( 65 men, 57 women )
Maraschin et al., Adv Exp Med Biol 2012 (Diabetes Mellitus, Type 1...) : The first worldwide accepted classification scheme for DM was published in 1979 by the National Diabetes Data Group ( NDDG ) and classified DM based on the pharmacologic therapy applied into two major groups : Insulin dependent diabetes mellitus ( IDDM ) and non-insulin dependent diabetes mellitus ( NIDDM )
McGuinness et al., Metabolism 1990 (Hyperinsulinism...) : Hyperinsulinemia and insulin resistance are commonly seen in obese and non-insulin dependent diabetes mellitis ( NIDDM ) patients
Yamasaki et al., Diabetes Res Clin Pract 1989 (Chronic Disease...) : In order to estimate the parameters of the model, an intravenous glucose infusion test ( GIT, 100 mg/kg.min x 2 min and 10 mg/kg.min x 118 min ) was carried out on 15 healthy subjects ( N ), 12 subjects with impaired glucose tolerance ( IGT ), 20 non-insulin dependent diabetics ( NIDDM ) and 13 patients with chronic pancreatitis ( CP )
Al-Muhtaseb et al., Diabetes Care 1989 (Diabetes Mellitus, Type 2) : The effects of insulin on the lipid values of nonobese non-insulin dependent diabetic ( NIDDM ) Arab women requiring insulin was investigated to find whether these patients have the same coronary artery risk factor related to lipid levels
Groop et al., J Clin Invest 1989 (Diabetes Mellitus, Type 2...) : The effect of graded, physiologic hyperinsulinemia ( +5, +15, +30, +70, +200 microU/ml ) on oxidative and nonoxidative pathways of glucose and FFA metabolism was examined in nine lean non-insulin dependent diabetic patients ( NIDDM ) and in eight age- and weight matched control subjects
Wasserman et al., Sports Med 1989 (Diabetes Mellitus) : In contrast, it appears that people with non-insulin dependent diabetes ( NIDDM ) can generally exercise without fear of a deleterious metabolic response
Boyko et al., Diabetes Care 1989 (Diabetes Mellitus, Type 2...) : We examined this association in a geographically based study among 551 residents of the San Luis Valley of Colorado and found no statistically significant increase in the relative risk of nasal S. aureus colonization in 188 non-insulin dependent diabetic ( NIDDM ) versus 363 nondiabetic subjects ( relative risk 1.3, 95 % confidence limits 0.9-1.8 )
Huang et al., Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association 1989 (Diabetes Mellitus, Type 2...) : To examine the relationship between HLA antigens and Type 2 non-insulin dependent diabetes ( NIDDM ), 72 patients were studied and compared with 282 controls
Wang et al., Zhonghua Yi Xue Za Zhi (Taipei) 1989 (Diabetes Mellitus, Type 2...) : Insulin clamp studies were carried out on 13 non-diabetics and 12 non-insulin dependent diabetics ( NIDDM )
Miyazaki et al., Endocrinol Jpn 1986 (Diabetes Mellitus, Type 2) : Basal plasma SLI levels in diet ( n = 8 ), sulfonyl urea ( n = 8 ), and insulin groups ( n = 8 ) of non-insulin dependent maturity onset diabetics ( NIDDM ) were 50 +/- 1.6, 59 +/- 4.5, and 74 +/- 5.8 pg/ml, respectively
Suzuki et al., Metabolism 1989 (Diabetes Mellitus, Type 2...) : By analytical ultracentrifugation, non-insulin dependent diabetic patients ( NIDDM ) with type IIa hyperlipoproteinemia (HLP) showed significantly higher incidence of multidisperse low density lipoprotein (LDL) than non-diabetics with type IIa HLP
Husband et al., Diabet Med 1986 (Diabetes Mellitus, Type 1...) : Forty-four non-insulin dependent diabetic ( NIDDM ) and 41 insulin dependent diabetic ( IDDM ) patients received GIK
Meadows et al., Diabet Med 1988 (Diabetes Mellitus, Type 1...) : Seventy-three per cent of insulin dependent diabetic patients ( IDDM ) and 92 % of non-insulin dependent diabetic patients ( NIDDM ) MCQ correct options had facility indices within the acceptable range of 30 to 90 %
Grenfell et al., Diabet Med 1988 (Diabetes Mellitus, Type 1...) : Reports of renal replacement therapy in diabetes usually refer to patients with insulin dependent diabetes mellitus ( IDDM ) only, and little is known about renal failure in non-insulin dependent diabetics ( NIDDM )
, Diabetes Res Clin Pract 1988 (Diabetes Mellitus, Type 1...) : The probands, who had been diagnosed as diabetic or glucose-intolerant earlier, included 21 patients with insulin dependent diabetes mellitus ( IDDM ), 56 with non-insulin dependent diabetes ( NIDDM ), one with an unknown type of diabetes, and nine with glucose intolerance
Wahlqvist et al., Diabetes Care 1988 (Diabetes Mellitus, Type 2) : Aortoiliac arterial wall compliance was measured in apparently healthy subjects and in patients with non-insulin dependent diabetes ( NIDDM ), on diet alone, who had no clinical evidence of peripheral arterial disease
Devlin et al., Diabetes 1987 (Diabetes Mellitus, Type 2...) : We studied glucose metabolism in non-insulin dependent diabetic ( NIDDM ) men with and without glycogen depleting cycle exercise 12 h beforehand and have compared the results to our previous data in lean and obese subjects
Groop et al., Diabetes Care 1987 (Diabetes Mellitus, Type 2...) : Fourteen non-insulin dependent diabetic ( NIDDM ) patients continued their previous medication ( 7 on glyburide, 7 on glipizide ) for 6 mo, after which they switched to the alternate treatment for another 6 mo
Laakso et al., Atherosclerosis 1988 (Body Weight...) : Coronary heart disease in insulin dependent ( IDDM ) and in non-insulin dependent diabetes ( NIDDM ) is associated with lipid and lipoprotein changes favouring atherosclerosis
Vijayasingam et al., Ann Acad Med Singapore 1988 (Diabetes Mellitus, Type 1...) : 10 were insulin dependent diabetics ( IDDM ), 24 insulin requiring and 66 non-insulin dependent diabetics ( NIDDM )
Keane et al., Diabetes Care 1988 (Bacteriuria...) : This study examined whether non-insulin dependent diabetic ( NIDDM ) subjects have an increased prevalence of asymptomatic bacteriuria compared with subjects with normal glucose tolerance
Madar et al., Eur J Clin Nutr 1988 (Diabetes Mellitus, Type 2) : The effect of fenugreek on postprandial glucose and insulin levels following the meal tolerance test ( MTT ) was studied in non-insulin dependent diabetics ( NIDDM )
Harris et al., Prim Care 1988 (Diabetes Mellitus) : Non-insulin dependent diabetes ( NIDDM ), also called type II diabetes, may remain relatively asymptomatic for years
Pyörälä et al., Diabete Metab 1987 (Arteriosclerosis...) : A few cross-sectional and still fewer prospective studies in patients with non-insulin dependent diabetes ( NIDDM ), including two ongoing studies carried out by our own research group, have shown associations between hyperinsulinaemia and the occurrence of ASVD, but these data still are far from consistent and conclusive
Haneda et al., Diabetes 1986 (Diabetes Mellitus, Type 1...) : We have studied the restriction fragment-length polymorphism in the 5'-flanking region of the human insulin gene in 47 nondiabetic Japanese subjects and in 52 subjects with non-insulin dependent diabetes ( NIDDM ) to elucidate the ethnic variation of the genetic polymorphism and its relationship with NIDDM
Reich et al., Metabolism 1986 (Diabetes Mellitus, Type 2) : Acceleration of glucose tolerance after repetitive intravenous glucose loads ( Staub-Traugott effect ) has not previously been tested in non-insulin dependent diabetes ( NIDDM )
Lins et al., Acta Med Scand 1986 (Diabetes Mellitus, Type 1...) : The rise in blood glucose in the control experiment was similar to that previously seen in non-insulin dependent diabetics ( NIDDM ) given the same xylose-glucose load
Freidenberg et al., J Clin Invest 1987 (Diabetes Mellitus, Type 2...) : The tyrosine kinase activity of the insulin receptor was examined with partially purified insulin receptors from adipocytes obtained from 13 lean nondiabetics, 14 obese nondiabetics, and 13 obese subjects with non-insulin dependent diabetes ( NIDDM )
Bruce et al., Med J Aust 1987 (Body Weight...) : In spite of maximal doses of sulphonylurea agents, patients with poorly controlled non-insulin dependent diabetes ( NIDDM ) often do not have improved metabolic control after the introduction of insulin therapy
Pories et al., Ann Surg 1987 (Body Weight...) : The gastric bypass favorably affected non-insulin dependent diabetes ( NIDDM ), hypertension, physical and role functioning, and several measures of mental health
Inoguchi et al., Diabetes Res Clin Pract 1986 (Diabetes Mellitus, Type 2...) : Plasma FN levels were measured in non-insulin dependent diabetics ( NIDDM ) ( n = 42 ) and compared with age matched control subjects ( n = 20 )
Ramachandran et al., Acta Diabetol Lat 1986 (Diabetes Mellitus, Type 2) : Errors in the assessment of glycemic control by clinicians, using the conventional method, based on random blood glucose and clinical parameters other than HbA1, were assessed in 125 non-insulin dependent diabetic ( NIDDM ) patients ( Group B )
King et al., Diabetes Res Clin Pract 1985 (Diabetes Mellitus, Type 2) : A comparison of 148 newly diagnosed ( ` incident ' ) and 202 previously diagnosed ( ` prevalent ' ) Nauruan diabetics, examined during a population survey in 1982, has permitted cautious inference regarding the natural history of non-insulin dependent diabetes ( NIDDM ) in this Micronesian population
Vincenzi et al., Minerva Med 1985 : The influence of Verapamil, a calcium antagonist, on circulating levels of glucose, insulin and glucagon has been evaluated in 5 normal subjects and in 5 patients with non insulin dependent diabetes ( NIDDM )
Kreines et al., Diabetes Care 1985 (Calcinosis...) : The present report is an analysis of the course of peripheral vascular disease ( PVD ) in 619 patients with non-insulin dependent diabetes ( NIDDM ) recruited within 1 yr of diagnosis and followed quarterly for up to 14 yr ( X = 10.5 yr )
Fajans et al., Adv Exp Med Biol 1985 (Diabetes Mellitus, Type 1...) : The recognition that Type I or insulin dependent diabetes ( IDDM ) and Type II or noninsulin dependent ( NIDDM ) differ from each other not only phenotypically but also in etiology and pathogenesis led the National Diabetes Data Group ( NDDG ) to devise the present nomenclature and classification of diabetes mellitus
Matsuda et al., Diabetes Res Clin Pract 1985 (Diabetes Mellitus, Type 1...) : Fasting SCPR did not differ between healthy subjects and sulfonylurea treated patients ( SU ) who were considered to have definite non-insulin dependent diabetes ( NIDDM ) ; but was significantly lower in patients with insulin dependent diabetes ( IDDM ) ( 0.24 +/- 0.10 ng/ml in IDDM vs. 1.43 +/- 0.61 ng/ml in SU, P less than 0.001 )
Dwyer et al., Diabetes Care 1985 (Blindness...) : The incidence rate of retinopathy was almost three times greater among residents with insulin dependent ( IDDM ) than with non-insulin dependent diabetes ( NIDDM ) ; however, the actual number of retinopathy cases was over four times greater among the more numerous residents with NIDDM
Ward et al., Diabetes Care 1984 (Diabetes Mellitus...) : The pathogenesis of the abnormal metabolic state in patients with non-insulin dependent diabetes ( NIDDM ) is controversial
Stefan et al., Diabetes 1982 (Diabetes Mellitus) : The application of immunofluorescence technique with anti-insulin, anti-glucagon, anti-somatostatin, and anti-pancreatic polypeptide (PP) antisera to sections of precisely sampled regions of the human pancreas allowed the quantitative evaluation of the total content of these four endocrine cell populations in 13 nondiabetics, in 2 insulin dependent diabetics ( IDDM ), and in 2 non-insulin dependent diabetic subjects ( NIDDM ) of various age and sex
Levitt et al., Diabetes Care 1980 (Diabetes Mellitus...) : We investigated the effects of fiber on responses of blood glucose, serum insulin, gastric inhibitory polypeptide (GIP), and immunoreactive pancreatic glucagon ( IRG ) to ingestion of mixed meal with and without added fiber ( 5 g guar and 5 g pectin ) in 12 normal, healthy subjects and in 12 age-, sex-, and weight matched non-insulin dependent , maturity-onset diabetic subjects ( NIDDM )
Rahier et al., J Clin Endocrinol Metab 1983 (Diabetes Mellitus) : Pancreases from insulin dependent diabetics ( IDDM ), noninsulin dependent diabetics ( NIDDM ), and nondiabetic subjects were analyzed by stereological and morphometrical methods in order to determine the weight of the lobe rich in pancreatic polypeptide (PP) cells in relation to the total weight of the pancreas and the volume density of PP cells in both parts of the gland, those rich and poor in PP cells
Giroix et al., Diabetes 1983 (Diabetes Mellitus, Experimental) : Non-insulin dependent diabetes ( NIDDM ) was obtained in adult rats following a neonatal streptozotocin injection
Lawson et al., Diabetes Care 1983 (Diabetes Complications...) : Both LJM and DC occurred not only in insulin dependent diabetes ( IDDM ) but also in non-insulin dependent diabetes ( NIDDM )
King et al., Diabetes Res 1984 (Body Weight...) : As defined by current WHO criteria, there was a total absence of non-insulin dependent diabetes ( NIDDM ) in these communities
Krassowski et al., Horm Metab Res 1984 (Diabetes Mellitus, Type 1) : L-Dopa induced a clear GH response in insulin dependent diabetes ( IDDM ) and in the control group while in non-insulin dependent diabetes ( NIDDM ) peak GH levels were lower ( P less than 0.05 ) and 4 of 7 subjects failed to respond to L-Dopa stimulation
King et al., Diabetes Care 1984 (Diabetes Mellitus...) : Non-insulin dependent diabetes ( NIDDM ) in a newly independent Pacific nation : the Republic of Kiribati ... A population based survey of 2938 subjects has demonstrated a high prevalence of non-insulin dependent diabetes ( NIDDM ) in the Micronesian population of Kiribati ( formerly the Gilbert Islands )
Hirata et al., Tohoku J Exp Med 1983 (Diabetes Mellitus...) : Among them, 198 were classified as insulin dependent diabetes ( IDDM ), 237 as non-insulin dependent diabetes ( NIDDM ), 12 were unclassified, and four were classified as other types
Wagener et al., Diabetes 1982 (Diabetes Mellitus...) : There is an increased risk to siblings of a diabetic ( 10.5 % ) in families where at least one parent has insulin dependent diabetes mellitus ( IDDM ) and also an increased risk to siblings of a diabetic ( 8.8 % ) when at least one parent has non-insulin dependent diabetes ( NIDDM )
Alberti et al., Diabetes Care 1982 (Diabetes Mellitus) : It is suggested that for major operations for well controlled non-insulin dependent diabetic ( NIDDM ) persons and for all minor and major operations for insulin dependent diabetic ( IDDM ) persons and poorly controlled NIDDM , a combined insulin ( 3.2 U/h ), glucose ( 10 g 10 % dextrose/h ), and potassium infusion should be used until oral feeding recommences
Gray et al., Diabetes 1980 (Diabetes Mellitus) : Plasma insulin, glucose, and insulin/glucose responses to a 50-g oral glucose tolerance test ( OGTT ) were compared in 14 islet cell antibody ( ICAb ) positive non-insulin dependent diabetics ( NIDDM ), 14 matched ICAb negative NIDDM, and 14 ICAb negative nondiabetic controls
Srikanta et al., J Clin Immunol 1981 (Diabetes Mellitus) : Pancreatic islet cell, thyroid, gastric parietal cell, and adrenal autoantibodies were studied in 110 young insulin dependent diabetics ( type I ; IDDM ), 12 non-insulin dependent diabetics ( NIDDM ), 26 patients with pancreatic diabetes, and 123 age- and sex matched healthy controls
Vaccaro et al., Artery 1982 (Arteriosclerosis...) : In order to elucidate this matter, at an early stage of the vascular complication, 54 non insulin dependent diabetic ( NIDDM ) patients, males, age range 40-59 years, without clinical signs of PA, were investigated by digital pulse plethysmography, measuring the inclination time ( IT ) of the pulse wave
Nielsen et al., Am J Kidney Dis 1995 (Albuminuria...) : In a prevalence cohort of all 50 albuminuric ( > or = 300 mg/24 hr ), non-insulin dependent diabetic mellitus ( NIDDM ) patients ( aged < 66 years ) attending a diabetic clinic during 1987, we identified four patients with acquired oligonephropathy who had developed diabetic nephropathy
Mathé et al., Diabete Metab 1995 (Diabetes Mellitus, Experimental...) : Models for non-insulin dependent diabetes ( NIDDM ) are obtained through selective breeding or dietary conditions
Girard et al., Diabete Metab 1995 (Diabetes Mellitus, Type 2...) : Non-insulin dependent diabetes ( NIDDM ) is characterized by overproduction of glucose, decreased effects of insulin on glucose utilization and production, and a defect in glucose induced insulin secretion
Ozben et al., Ann Clin Biochem 1995 (Diabetes Mellitus, Type 2) : Urinary excretions of albumin, glycosaminoglycans ( GAGS ), total sialic acid (TSA), and lipid associated sialic acid ( LASA ) were measured in 78 non-insulin dependent diabetic patients ( NIDDM ) and 28 healthy subjects
Nakanishi et al., Metabolism 1993 (Diabetes Mellitus, Type 1) : Both pancreatic exocrine glands and beta cells were markedly reduced in weight in IDDM patients compared with non-insulin dependent diabetic ( NIDDM ) patients or nondiabetic controls
Virtanen et al., Ann Med 1994 (Diabetes Mellitus, Type 1...) : Quite different nutrition related environmental factors influence the development of type 1 insulin dependent diabetes ( IDDM ) and type 2 non-insulin dependent diabetes ( NIDDM )
Potts et al., J Clin Epidemiol 1994 (Diabetes Mellitus, Type 2...) : South Asians ( Asians ) have a high prevalence of non-insulin dependent diabetes ( NIDDM ) and a high incidence of ischaemic heart disease ( IHD )
Vaag et al., Diabetologia 1995 (Diabetes Mellitus, Type 2...) : Non-insulin dependent diabetic ( NIDDM ) patients were studied during a modified euglycaemic state when fasting hyperglycaemia was normalized by a prior ( -210 to -150 min ) -- and later withdrawn ( -150-0 min ) -- intravenous insulin infusion
Kuusi et al., Eur J Clin Invest 1995 (Diabetes Mellitus, Type 2) : In order to evaluate whether Lp(a), a lipoprotein that is potentially thrombogenic and atherogenic, is a potential risk factor for CAD in non-insulin dependent diabetes ( NIDDM ), we compared the Lp(a) and its distribution in 145 NIDDM patients with that in 94 healthy control subjects
Lehmann et al., Ther Umsch 1994 (Autoimmune Diseases...) : Noninsulin dependent diabetes mellitus ( NIDDM ) is a complex disorder characterized by insulin resistance and impaired insulin secretion and is associated with an increased risk of coronary heart disease, peripheral vascular disease, arterial hypertension and dyslipidemia
Wasada et al., Diabetes Res Clin Pract 1994 (Cardiovascular Diseases...) : To investigate whether a resistance to insulin stimulated glucose uptake ( IR ) is associated with the risk factors ( RF ) for cardiovascular disease ( CVD ) in non-insulin dependent diabetic ( NIDDM ) patients, we determined the degree of IR in 135 adult NIDDM patients who had no advanced diabetic complications
Uccioli et al., Diabetologia 1994 (Diabetes Mellitus, Type 2...) : Since the autonomic nervous system influences peripheral circulation, we studied the relationship between autonomic neuropathy and foot transcutaneous oxymetry in non-insulin dependent diabetic ( NIDDM ) patients without peripheral vascular disease
Hirata et al., Diabetes Res Clin Pract 1994 (Diabetes Mellitus, Type 1...) : One group of patients with non-insulin dependent diabetes ( NIDDM ) was followed up in Osaka and the other group in Tokyo
O'Rahilly et al., Lancet 1994 (Diabetes Mellitus, Type 2...) : Non-insulin dependent diabetes ( NIDDM ) is a heterogeneous state involving various degrees of beta-cell dysfunction and insulin resistance, although the relative importance of these two factors is controversial
Dryden et al., Eur J Clin Invest 1994 (Obesity) : Obesity has well-known associations with non-insulin dependent diabetes ( NIDDM ), hypertension, dyslipidaemia and coronary heart disease, as well as less obvious links with diseases such as osteoarthrosis and various malignancies ; it also causes considerable problems through reduced mobility and decreased quality of life
Shore et al., Diabetes 1994 (Diabetes Mellitus, Type 2) : Although patients with non-insulin dependent diabetes mellitus ( NIDDM ) and insulin dependent diabetes NIDDM ) develop a similar range of microvascular complications, differences in their expression and prevalence suggest that different pathogenic mechanisms may be operational
McGarry et al., J Cell Biochem 1994 (Diabetes Mellitus...) : With emphasis on non-insulin dependent diabetes ( NIDDM ), three possibilities are explored here : ( 1 ) that the insulin resistance characteristic of obesity/NIDDM syndromes is the result rather than the cause of hyperinsulinemia, as is widely held, ( 2 ) that the linkage between hyperactivity of the pancreatic beta-cell and peripheral insulin resistance is vested in excessive delivery of lipid substrate from liver to the muscle bed, and ( 3 ) the conceivably hyperamylinemia works in concert with hyperinsulinemia in promoting overproduction of very-low-density lipoproteins by the liver, and thus in the etiology of muscle insulin resistance
Horita et al., Atherosclerosis 1994 (Albuminuria...) : The association of apolipoprotein E (apo E) genetic polymorphism, particularly apo E2, with renal failure ( plasma creatinine > or = 1.4 mg/dl, and urinary albumin excretion index > or = 300 mg/g.creatinine and/or persistent proteinuria ) was investigated in 57 non-insulin dependent diabetic ( NIDDM ) patients
Steiner et al., J Intern Med Suppl 1994 (Coronary Disease...) : This may be as a part of the syndrome of insulin resistance or in diabetes, particularly non-insulin dependent diabetes ( NIDDM )
Manzato et al., J Intern Med Suppl 1994 (Diabetes Mellitus, Type 2...) : The prevalence of hypercholesterolaemia is similar in non-insulin dependent diabetic ( NIDDM ) patients and in non-diabetic subjects
Dowse et al., Diabetes Res Clin Pract 1994 (Diabetes Mellitus, Type 1...) : Antibodies to glutamic acid decarboxylase ( anti-GAD ) are common in typical insulin dependent diabetes mellitus, and also identify a sub-group of older persons who are originally misdiagnosed as having non-insulin dependent disease ( NIDDM )
Raucoules-Aimé et al., Br J Anaesth 1994 (Diabetes Mellitus, Type 1...) : We have compared intraoperative glycaemic control, insulin requirements and metabolic and endocrine variables in 40 non-insulin dependent diabetic patients ( NIDDM ) and 40 insulin dependent diabetic patients ( IDDM ) undergoing general anaesthesia for elective procedures
Farrer et al., Diabetes Res Clin Pract 1994 (Diabetes Mellitus, Type 2...) : The clinical efficacy of the 3-hydroxy-3-methyl-glutaryl-coenzyme A ( HMGCoA) reductase inhibitor simvastatin in the treatment of hypercholesterolaemia in non-insulin dependent diabetes ( NIDDM ), was examined in a double-blind placebo controlled study of 6 months in 70 patients with NIDDM ( age 25-70 years ), of whom 57 were randomised to placebo ( 29 patients ) or simvastatin for 6 months, following a 3-month run-in on diet
Chan et al., J Hum Hypertens 1994 (Albuminuria...) : A total of 78 Chinese patients with clinically uncomplicated non-insulin dependent diabetes ( NIDDM ) who had plasma creatinine concentrations of < 150 mumol/l were studied. Antihypertensive treatment was discontinued for at least six weeks prior to measurements of routine biochemistry, proteinuria, plasma atrial natriuretic peptide (ANP) concentrations and components of the renin-angiotensin-aldosterone system ( RAAS ). BP was measured on three occasions during the six weeks period prior to these measurements. At the end of the six week period, a total of 33 patients had definite hypertension ( supine BP > or = 160/95 mmHg )
Lau et al., J Formos Med Assoc 1993 (Diabetes Mellitus, Type 2...) : We investigated both sodium-lithium countertransport ( Na-Li CT ) and ouabain-sensitive sodium transport ( Na pump ) of erythrocytes in healthy subjects ( group A ), patients with non-insulin dependent diabetes ( NIDDM ) without nephropathy ( group B ), patients in the proteinuric stage ( group C ), and those in the renal insufficiency stage ( group D )
Milne et al., Diabetes Care 1994 (Body Weight...) : To compare three sets of dietary guidelines for the treatment of non-insulin dependent diabetes ( NIDDM ) in free living individuals and to observe the effects on metabolic control over an 18-month period
Reppas et al., Diabetes Res Clin Pract 1993 (Diabetes Mellitus, Type 2) : The ability of high viscosity hydroxypropylmethylcellulose ( HPMC ) to reduce postprandial glucose concentrations was assessed in patients with non-insulin dependent diabetes ( NIDDM ) and healthy volunteers
Lerman Garber et al., Arch Inst Cardiol Mex 1993 (Diabetes Mellitus, Type 2...) : Previous reports suggest that morbidity and mortality post acute myocardial infarction ( AMI ) are increased in patients with non-insulin dependent diabetes ( NIDDM )
Gradman et al., J Am Geriatr Soc 1993 (Diabetes Mellitus, Type 2) : To determine whether cognitive function improves with improved glycemic control in older subjects with non-insulin dependent diabetes ( NIDDM )
Laws et al., J Intern Med 1993 (Diabetes Mellitus, Type 2...) : To evaluate lipids and lipoproteins as risk factors for coronary heart disease (CHD) in older men with non-insulin dependent diabetes ( NIDDM ) or abnormal glucose tolerance compared with normoglycaemic men
Cockram et al., Diabetes Res Clin Pract 1993 (Diabetes Mellitus...) : Our data further confirm that Hong Kong Chinese have a moderate to high susceptibility to non-insulin dependent diabetes ( NIDDM ) when exposed to sufficient environmental and lifestyle factors
Newgard et al., Diabetes 1994 (Diabetes Mellitus, Type 1...) : In diabetes, insulin secretion is either completely absent ( insulin dependent diabetes mellitus [ IDDM ] ) or inappropriately regulated ( non-insulin dependent diabetes mellitus [ NIDDM ] )
Wilson et al., J Clin Invest 1993 (Diabetes Mellitus, Type 2...) : A proband with chylomicronemia, pancreatitis, and non-insulin dependent diabetes ( NIDDM ) bears two different mutations in exon 3 of the lipoprotein lipase (LPL) gene : a missense mutation, 75Arg -- > Ser, inherited through the paternal line and a truncation, 73Tyr -- > Ter, through the maternal line
Fassberg et al., J Fam Pract 1993 (Diabetes Mellitus, Type 2...) : First, from a medical point of view, insulin has a lipogenic effect and may actually contribute to weight gain, hyperinsulinemia, and increased insulin resistance in obese patients with NIDDM
Collo et al., Nurse Pract 1993 (Diabetes Mellitus, Type 2) : Clinicians are frequently faced with treating non-insulin dependent diabetics ( NIDDM ) who do not exhibit optimal glycemic control on maximal dosages of oral sulfonylurea agents or large dosages of insulin
Leibel et al., Crit Rev Food Sci Nutr 1993 (Obesity) : Such studies may ultimately lead to the characterization of genes that influence the development and severity of obesity and non-insulin dependent diabetes ( NIDDM ) in humans
Reenders et al., Fam Pract 1993 (Diabetes Mellitus, Type 1...) : During one year 19 GPs in the area of Hoogeveen in the Netherlands examined their non-insulin dependent ( NIDDM ) patients, including those under specialist 's care
Laakso et al., Circulation 1993 (Coronary Disease...) : The aim of this study was to investigate the association of lipoprotein fractions with the future risk of coronary heart disease (CHD) in patients with non-insulin dependent diabetes ( NIDDM )
O'Byrne et al., Clin Pharmacokinet 1993 (Diabetes Mellitus, Type 1...) : We also examined protein binding of warfarin and lidocaine in 30 patients with non-insulin dependent diabetes ( NIDDM ) and 25 controls
Wettre et al., Scand J Clin Lab Invest 1993 (Diabetes Mellitus, Type 2) : Blood glucose profiles, fasting blood glucose and glycated haemoglobin were followed prospectively for 6 weeks in 14 patients with non-insulin dependent diabetes ( NIDDM )
Rasmussen et al., Metabolism 1993 (Diabetes Mellitus, Type 2) : The study objective was to determine the dose-response relationships between postprandial blood glucose, insulin, and glucagon responses and the amount of starch ingested in non-insulin dependent diabetic ( NIDDM ) subjects
Chan et al., Postgrad Med J 1993 (Albuminuria...) : In the remaining 397 patients with non-insulin dependent diabetes ( NIDDM ), the mean ( s.d. ) body mass index ( BMI ) was 24.4 +/- 3.2 kg/m2 in females and 24.2 +/- 3.2 kg/m2 in males
Yudkin et al., J Diabetes Complications 1993 (Diabetes Mellitus, Type 2...) : Use of such assays may help clarify the role of insulin deficiency in non-insulin dependent diabetes mellitus ( NIDDM )
Shigetomi et al., Hypertens Res 1995 (Diabetes Mellitus, Type 2) : Patients with non-insulin dependent diabetic ( NIDDM ), a protein induced increase in Ccr was comparable to that in C, while FEN+ did not change following protein
Crepaldi et al., Diabetes Res Clin Pract 1995 (Diabetes Mellitus, Type 2...) : NIDDM is the result of concomitant defects in both insulin secretion and insulin action
Clark et al., Diabetes Res Clin Pract 1995 (Chronic Disease...) : Pancreatic pathology in non-insulin dependent diabetes ( NIDDM )
Tattersall et al., Diabetes Res Clin Pract 1995 (Diabetes Mellitus, Type 2...) : Non-insulin dependent diabetes ( NIDDM ) is a common multimetabolic disorder with potential ( and potentially severe ) long-term complications affecting large and small blood vessels
Rothschild et al., Genomics 1995 (Diabetes Mellitus, Type 2...) : Amplification using FBP exon-specific primers with a YAC contig from this region of chromosome 9 further refined the placement of FBP genomic sequences to an approximately 1.7-cM region flanked by D9S280 and D9S287, near the gene for Fanconi anemia group C. Precise localization of the FBP gene enabled evaluation of FBP as a candidate gene for maturity-onset diabetes of the young ( MODY ) and non-insulin dependent diabetes ( NIDDM ) in both Caucasian and African-American families, using the highly informative markers D9S287 and D9S176
Standl et al., Clin Invest Med 1995 (Arteriosclerosis...) : Studies of macrovascular disease in non-insulin dependent diabetes ( NIDDM ) have shown a significant increase in peripheral vascular, coronary, and carotid artery disease in diabetics compared to non-diabetics
Rett et al., J Hypertens Suppl 1995 (Diabetes Mellitus, Type 2...) : BACKGROUND : Since it is not yet clear whether and to what degree treatment of mild hypertension will decrease cardiovascular morbidity and mortality in non-insulin dependent diabetes ( NIDDM ), decisions concerning the treatment of hypertension diabetics are at present based on data from the non-diabetic population
Horiuchi et al., Nihon Ronen Igakkai Zasshi 1995 (Diabetes Mellitus, Type 2...) : Moreover we divided non-insulin dependent diabetic patients ( NIDDM ) into two groups ; the high BMD group and the low BMD group
Shimizu et al., Thromb Haemost 1995 (Albuminuria...) : Plasma thrombin-anti-thrombin III complex (TAT) levels, representing a functional state of clotting system, were studied in one hundred and fifteen non-insulin dependent diabetic ( NIDDM ) patients
Larsen et al., Eur J Clin Nutr 1996 (Diabetes Mellitus, Type 2) : To study the influence of parboiling, amylose content and gelatinisation temperature of rice on the postprandial blood glucose and insulin responses in non-insulin dependent diabetic ( NIDDM ) subjects
Ito et al., Proc Soc Exp Biol Med 1996 (Diabetes Mellitus, Type 2...) : Elevated plasma levels of plasminogen activator inhibitor-1 ( PAI-1 ) have been shown to be a risk factor for the development of vascular complications in obese and hyperinsulinemic non-insulin dependent diabetes ( NIDDM ) patients
Collins et al., Diabet Med 1996 (Cardiovascular Diseases...) : Risk factors for all-cause and cardiovascular disease ( CVD ) mortality in subjects with non-insulin dependent diabetes ( NIDDM ) are also described
Chan et al., Diabet Med 1996 (Albuminuria...) : Albuminuria, insulin resistance and dyslipidaemia in Chinese patients with non-insulin dependent diabetes ( NIDDM ) ... In order to examine relationships between albuminuria, insulin resistance, and dyslipidaemia in non-insulin dependent diabetes ( NIDDM ), we studied 164 Chinese patients ( 68 men, 96 women ), treated with diet or oral hypoglycaemic agents, on three occasions during a 6-week period
Ciaraldi et al., J Clin Invest 1995 (Diabetes Mellitus, Type 2...) : As previously reported, cells cultured from non-insulin dependent diabetic ( NIDDM ) subjects displayed significant reductions in both basal and acute insulin stimulated transport compared to nondiabetic controls ( NC )
Kelley et al., J Clin Invest 1996 (Diabetes Mellitus, Type 2...) : Insulin stimulation of the rate constant for glucose phosphorylation was similar in obese and lean subjects but reduced in NIDDM
Martinka et al., Vnitr Lek 1996 (Diabetes Mellitus, Type 2...) : Most of the authors suggest that NIDDM is caused primarily by insulin resistance (IR) ( which is also considered an earliest detectable defect ) with subsequent inability of the pancreas sufficiently compensate for IR
Vestergaard et al., Diabetologia 1995 (Diabetes Mellitus, Type 2...) : We have previously shown that the mRNA expression of muscle glycogen synthase is decreased in non-insulin dependent diabetic ( NIDDM ) patients ; the objective of the present protocol was to examine whether the gene expression of muscle glycogen synthase in NIDDM is affected by chronic sulphonylurea treatment
Blyth et al., J Hand Surg Br 1996 (Diabetes Mellitus, Type 1...) : Eighteen of the 100 patients were diabetic with six insulin dependent diabetics ( IDDM ) and 12 non-insulin dependent diabetics ( NIDDM )
Mooradian et al., Drugs 1996 (Diabetes Mellitus, Type 2) : Non-insulin dependent diabetes ( NIDDM ) is a common problem in the elderly
Leibowitz et al., Diabetologia 1996 (Cardiovascular Diseases...) : Non-insulin dependent diabetic ( NIDDM ) patients show a high incidence of cardiovascular disease, with greater risk of recurrent myocardial infarction and a less favourable clinical outcome than non-diabetic patients
Lahdenperä et al., Diabetologia 1996 (Coronary Disease...) : An increase of low-density lipoprotein triglycerides ( LDL-Tg ) was found to be an independent coronary artery disease ( CAD ) risk factor for non-insulin dependent diabetic ( NIDDM ) patients in a recent prospective study
Kumar et al., Diabetologia 1996 (Diabetes Mellitus, Type 2) : The effects of troglitazone, a novel thiazolidinedione, in non-insulin dependent diabetic ( NIDDM ) patients were studied in a double-blind, parallel-group, placebo controlled, dose ranging trial
Trevisan et al., Diabetologia 1996 (Albuminuria...) : To test whether a similar abnormality is present in fibroblasts from non-insulin dependent diabetic ( NIDDM ) patients with microalbuminuria and hypertension, we examined intracellular pHi and Na+/H+ antiport activity, using the pH sensitive dye 2 ', 7'-bis ( 2-carboxyethyl-5 ( 6 ) -carboxyfluorescein ( BCECF ), in cultured skin fibroblasts obtained from 34 NIDDM patients, divided into four groups based upon whether they had microalbuminuria or hypertension, or both : Group 1, nine NIDDM patients with microalbuminuria and hypertension
Adler et al., Diabet Med 1996 (Diabetes Mellitus, Type 2...) : The once low prevalence of non-insulin dependent ( Type 2 ) diabetes ( NIDDM ) in Eskimos and Indians has risen approximately fourfold over the past 30 years, suggesting the presence of a non-genetic factor affecting NIDDM prevalence
Toplak et al., Diabetes Res Clin Pract 1996 (Diabetes Mellitus, Type 2) : Despite the fact that diabetes is accompanied by increased risk for infections, no data on chlamydial infections in the non-insulin dependent diabetic ( NIDDM ) patient exist
Kasperska-Czyzyk et al., Diabetologia 1996 (Diabetes Mellitus, Type 2) : The 75-g oral glucose tolerance test was performed in 38 normoglycaemic ( World Health Organization criteria ) non-diabetic volunteers, aged 31-40 years, of whom 20 had a non-insulin dependent diabetic ( NIDDM ) mother and 18 had an NIDDM father
Kasuga et al., J Autoimmun 1996 (Diabetes Mellitus, Type 2) : It was recently reported that antibodies against glutamic acid decarboxylase ( GADAb ) have a high positive predictive value for insulin-dependency in non-insulin dependent diabetic ( NIDDM ) patients
Kadiki et al., Diabetes Res Clin Pract 1996 (Diabetes Mellitus, Type 1...) : Incidence of insulin dependent diabetes ( IDDM ) and non-insulin dependent diabetes ( NIDDM ) ( 0-34 years at onset ) in Benghazi, Libya ... The incidence of insulin dependent diabetes ( IDDM ) and non-insulin dependent diabetes ( NIDDM ) in Benghazi, Libya in the < 35-year age group during the period 1981-1990 are reported. Incidence data for IDDM were based on prospective registration of patients while incidence data for NIDDM were based on analysis of files. Case ascertainment of IDDM cases was estimated to be > 95 %
Pyörälä et al., Ann Med 1996 (Coronary Artery Disease...) : The incidence of atherosclerotic vascular disease is greatly increased in patients with non-insulin dependent diabetes ( NIDDM )
Cooper et al., Diabet Med 1996 (Diabetes Mellitus, Type 2...) : Postprandial lipid profiles and release of insulin (INS), intact proinsulin ( PI ), and 32-33 split proinsulin (SPI) in response to a mixed meal with a high fat content were determined over a 12 h period in non-obese control subjects ( n = 10 ) and non-insulin dependent ( Type 2 ) diabetic ( NIDDM ) patients with normotriglyceridaemia ( NTG ; n = 11 ) and hypertriglyceridaemia ( HTG ; n = 10 ), by calculation of the ` areas under the curves ' ( AUC )
Durlach et al., Diabetes Metab 1996 (Diabetes Mellitus, Type 2...) : Variations in serum Lp(a) concentrations were studied in a large population of non-insulin dependent diabetic ( NIDDM ) patients in relation to long-term complications
Wasada et al., Intern Med 1995 (Diabetes Mellitus, Type 2...) : We report four non-insulin dependent diabetic ( NIDDM ) patients accompanied by a unique combination of sick sinus syndrome ( SSS ) and hyperinsulinemia of unknown etiology
Standl et al., Diabetologia 1996 (Cardiovascular Diseases...) : The 10-year follow-up of the Munich General Practitioner Project was designed as a long-term prospective study to evaluate factors predicting macrovascular and overall mortality in a random cohort of non-insulin dependent diabetic ( NIDDM ) patients
Nauck et al., Diabetologia 1996 (Diabetes Mellitus, Type 2) : Intravenous glucagon-like peptide (GLP)-1 [ 7-36 amide ] can normalize plasma glucose in non-insulin dependent diabetic ( NIDDM ) patients
Fioretto et al., Diabetologia 1996 (Albuminuria...) : Microalbuminuria predicts overt nephropathy in non-insulin dependent diabetic ( NIDDM ) patients ; however, the structural basis for this functional abnormality is unknown
Lind et al., Diabetologia 1996 (Cardiomyopathies...) : After the exclusion of subjects with coronary heart disease or those on regular antihypertensive treatment, 30 normotensive subjects with diabetes were compared with 10 subjects with non-insulin dependent diabetes ( NIDDM ) and a diastolic blood pressure 90 mm Hg or more and 203 normotensive control subjects with normal glucose tolerance
Nyengaard et al., Diabetologia 1996 (Birth Weight...) : These studies were undertaken to ascertain if there is any association between low birth weight, and low kidney weight, few and/or small glomeruli, in kidneys from a control group and a group of non-insulin dependent diabetic ( NIDDM ) patients
Olsen et al., Diabetologia 1996 (Diabetes Mellitus, Type 2...) : According to extensive autopsy studies, non-diabetic renal disease seems to be rare in diabetes mellitus, but recent publications suggest a significant prevalence of non-diabetic renal disease in non-insulin dependent diabetic ( NIDDM ) patients, especially in the absence of retinopathy
Liesenfeld et al., Int J Qual Health Care 1996 (Diabetes Complications...) : The documentation was incomplete ; e.g. in 8.0 % of insulin dependent ( IDDM ) and in 26.4 % of non-insulin dependent diabetics ( NIDDM ), HbA1c was missing
Gohdes et al., Diabetes Res Clin Pract 1996 (Diabetes Mellitus, Type 2) : American Indians and Alaska Natives have experienced rapidly increasing rates of non-insulin dependent diabetes ( NIDDM )
Attia et al., Eur J Clin Invest 1997 (Diabetes Mellitus, Type 2) : Retarded post-prandial ( pp ) lipid clearance is potentially a major component of the increased cardiovascular risk incurred by hypertriglyceridaemic non-insulin dependent diabetic mellitus ( NIDDM ) patients
Henricsson et al., Diabet Med 1997 (Blindness...) : To study the progression of diabetic retinography in relation to diabetes treatment and glycaemic control in patients with non-insulin dependent ( Type 2 ) diabetes mellitus ( NIDDM ), we performed a prospective study in a cohort of 1378 diabetic patients, aged > or = 40 years at diagnosis, of whom 333 were treated with insulin, and 1045 with oral antihyperglycaemic agents or diet alone
Gougeon et al., Am J Clin Nutr 1997 (Body Weight...) : We postulated whether interventions capable of restoring euglycemia would correct whole-body protein metabolism, shown previously to be elevated in hyperglycemic persons with non-insulin dependent diabetes ( NIDDM )
D'Argenzio et al., Minerva Endocrinol 1996 (Body Weight...) : In the treatment of type 2 or non-insulin dependent diabetes ( NIDDM )
Steiner et al., Diabetologia 1996 (Coronary Artery Disease...) : The largest number of those who have coronary artery disease have non-insulin dependent diabetes ( NIDDM )
Passa et al., Diabetologia 1996 (Albuminuria...) : Microalbuminuria and proteinuria are strong independent predictors for increased cardiovascular mortality in non-insulin dependent diabetic ( NIDDM ) patients
Cerasi et al., Diabetes Metab 1997 (Diabetes Mellitus, Type 2...) : It has been debated for the past two decades whether non-insulin dependent diabetes mellitus ( NIDDM ) is caused by insulin deficiency or insulin resistance
Larsen et al., Diabetologia 1997 (Diabetes Mellitus, Type 2) : The influence of exercise on glycaemia in the post-prandial state was studied for the first time in non-insulin dependent diabetic ( NIDDM ) patients
Leslie et al., Diabet Med 1997 (Diabetes Mellitus, Type 1...) : It is well established that peripheral insulin sensitivity is a critical factor in the aetiology of non-insulin dependent ( Type 2 ) diabetes mellitus ( NIDDM )
Fernando et al., Br J Rheumatol 1997 (Diabetes Mellitus, Type 2...) : Two hundred and sixteen patients with non-insulin dependent diabetes ( NIDDM ) and 216 age- and gender matched controls were studied to assess the prevalence of limited joint mobility ( LJM )
Farkas et al., Orv Hetil 1997 (Albuminuria...) : After applying exclusion criteria data of 933 diabetic patients [ 129 insulin dependent ( IDDM ) and 804 non-insulin dependent ( NIDDM ) patients ; 424 men, 509 women ] were analysed
Migdalis et al., J Med 1996 (Albuminuria...) : The aim of this study was to access the associations between urinary albumin excretion rate (AER) and diabetic retinopathy and its major risk factors in 105 type II non-insulin dependent diabetic ( NIDDM ) patients
Gatenby et al., Diabet Med 1996 (Diabetes Mellitus, Type 2) : Fourteen patients with non-insulin dependent diabetes ( NIDDM ) attended the study centre on 4 mornings separated by at least 3 days, to receive in random order 75 g carbohydrate breakfast meals of control or guar breads with jam and butter
Mohamed-Ali et al., Diabet Med 1997 (Diabetes Mellitus, Type 2...) : In non-insulin dependent ( Type 2 ) diabetes mellitus ( NIDDM ), however, insulin concentrations and insulin resistance are less closely associated
Leoncini et al., Thromb Res 1997 (Diabetes Mellitus, Type 2...) : 28 non insulin dependent diabetic subjects ( NIDDM ) were examined
Astorri et al., Clin Cardiol 1997 (Diabetes Mellitus, Type 1...) : Twenty insulin dependent diabetic ( IDDM ) patients, 10 non-insulin dependent diabetic ( NIDDM ) patients, and 12 healthy individuals ( C ) as controls, matched for age, gender, and without overt cardiovascular disease, were assessed in this study
Hirano et al., Diabetes Res Clin Pract 1997 (Albuminuria...) : Because a substantially high incidence of cardiovascular disease has been reported in diabetic patients with nephropathy compared with those without nephropathy, we measured plasma levels of PAI-1, FVII activity and fibrinogen in non-insulin dependent diabetic patients ( NIDDM ) with normoalbuminuria ( without nephropathy ), microalbuminuria ( incipient nephropathy ) and macroalbuminuria ( overt nephropathy )
Ruhnau et al., Diabetes Res Clin Pract 1997 (Diabetes Mellitus, Type 2...) : Measurement of glycosuria is still widely used for home monitoring of glycaemia control in non-insulin dependent diabetes ( NIDDM )
Arkkila et al., J Diabetes Complications 1997 (Arteriosclerosis...) : Limited joint mobility in non-insulin dependent diabetic ( NIDDM ) patients : correlation to control of diabetes, atherosclerotic vascular disease, and other diabetic complications ... This study examined the association between limited joint mobility ( LJM ) and diabetic control, atherosclerotic vascular disease and other diabetic complications in non-insulin dependent diabetic ( NIDDM ) patients
Vilbergsson et al., Diabet Med 1997 (Diabetes Mellitus, Type 2) : This is the first large survey carried out in Iceland to estimate the prevalence and incidence of known and unknown non-insulin dependent ( Type 2 ) diabetes ( NIDDM ) among males and females, aged 34-79
Zouvanis et al., Diabet Med 1997 (Diabetes Mellitus...) : Thirty-two of the patients with DKA ( 55.2 % ) were classified as having non-insulin dependent ( Type 2 ) diabetes mellitus ( NIDDM )
Mizuno et al., Metabolism 1997 (Diabetes Mellitus, Type 2) : To clarify the mechanism ( s ) of the antidiabetic effects of truncated glucagon-like peptide-1 (GLP-1) in diabetics, we examined its insulinotropic and extrapancreatic effects in a newly established strain of spontaneously non-insulin dependent diabetic ( NIDDM ) rats, Otsuka Long-Evans Tokushima Fatty ( OLETF ) rats, that received a continuous infusion of truncated GLP-1 620 pmol/d/kg ( G group, n = 12 ) or of vehicle ( V group, n = 12 ) for 4 weeks by Alzet pump
Faronato et al., Diabetologia 1997 (Albuminuria...) : Proteinuria and nephropathy have been found to cluster in families of non-insulin dependent diabetic ( NIDDM ) Pima Indian, and in Caucasian insulin dependent diabetic ( IDDM ) patients
Kurbel et al., Med Hypotheses 1997 (Diabetes Mellitus, Type 2...) : Our simulation model assumes that the defective insulin binding receptors in non-insulin dependent diabetes ( NIDDM ) patients result from functional receptor recycling
Nielsen et al., Scand J Clin Lab Invest 1997 (Diabetes Mellitus, Type 2...) : Endothelial dysfunction is a prevalent phenomenon in non-insulin dependent diabetic ( NIDDM ) patients with hypertension and albuminuria, and may contribute to the development and progression of cardiovascular disease, which is the main cause of the high morbidity and mortality observed in these patients
Gorden et al., Ann Acad Med Singapore 1997 (Diabetes Mellitus, Type 2) : In 1959, the radioimmunoassay of Yalow and Berson solidified the concept of insulin resistance in non-insulin dependent diabetes ( NIDDM )
Zander et al., Exp Clin Endocrinol Diabetes 1997 (Albuminuria...) : 1025 non-insulin dependent ( Type 2 ) diabetics ( NIDDM ) of both sexes were investigated
Nilsson et al., Exp Clin Endocrinol Diabetes 1997 (Cardiovascular Diseases...) : Several pathophysiological mechanisms link hypertension with non-insulin dependent diabetes ( NIDDM ), e.g. insulin resistance
Rattarasarn et al., Diabetes Res Clin Pract 1997 (Diabetes Mellitus, Type 2) : The objective of this study was to determine the frequency of glutamic acid decarboxylase antibody ( GAD-Ab ) in Thai non-insulin dependent diabetes ( NIDDM ) patients who had secondary sulfonylurea failure
Humphriss et al., Diabetologia 1997 (Diabetes Mellitus, Type 2...) : Non-diabetic first degree relatives of non-insulin dependent diabetic ( NIDDM ) families are at increased risk of developing diabetes mellitus, and have been studied to identify early metabolic abnormalities
Vijay et al., Diabet Med 1997 (Albuminuria...) : Non-insulin dependent ( Type 2 ) diabetes mellitus ( NIDDM ) and long-term complications such as nephropathy have a strong genetic predisposition
de Sonnaville et al., Diabetologia 1997 (Diabetes Mellitus, Type 2) : In primary care it is difficult to treat the growing number of non-insulin dependent diabetic ( NIDDM ) patients according to ( inter ) national guidelines
Brocco et al., Kidney Int Suppl 1997 (Albuminuria...) : We have recently described heterogeneity in renal structure in non-insulin dependent diabetic patients ( NIDDM ) with microalbuminuria ( MA ; defined as albumin excretion rate from 20 to 200 micrograms/min )
Thai et al., Diabetologia 1997 (Diabetes Mellitus, Type 1...) : In non-insulin dependent diabetic ( NIDDM ) patients, it has been suggested that the presence of GADab may identify a subset of latent autoimmune diabetes in adults ( LADA )
Henriksen et al., Diabetologia 1997 (Diabetes Mellitus, Type 2...) : Oral glucose tolerance ( OGTT ) and intravenous glucose tolerance tests with minimal model analysis were performed before and following 5 days of dex treatment ( 4 mg/day ) in 20 relatives of non-insulin dependent diabetic ( NIDDM ) patients and in 20 matched control subjects ( age : 29.6 +/- 1.7 vs 29.6 +/- 1.6 years, BMI : 25.1 +/- 1.0 vs 25.1 +/- 0.9 kg/m2 )
Clodi et al., Diabetologia 1997 (Diabetes Mellitus, Type 2...) : Lp(a), one of the most atherogenic lipoproteins, is believed to contribute significantly to vascular diseases in non-insulin dependent diabetic ( NIDDM ) patients
Smith et al., Diabet Med 1997 (Diabetes Mellitus, Type 1...) : In a Hong Kong Chinese population we have detected the 3243 mutation in 2 of 74 unrelated subjects with well characterized insulin dependent ( Type 1 ) diabetes mellitus ( IDDM ) and 2 of 75 unrelated subjects with young onset ( < 35 years ) non-insulin dependent diabetes ( NIDDM )
Dijkstra et al., Diabet Med 1997 (Burns...) : We describe six patients with non-insulin dependent ( Type 2 ) diabetes mellitus ( NIDDM ) and thermal foot injury admitted to the Burn Centre in Rotterdam
Nitiyanant et al., J Med Assoc Thai 1997 (Diabetes Mellitus, Type 2) : This study was aimed to evaluate the efficacy and safety of gliquidone, the latest available sulphonylurea, as a monotherapy for patients with non-insulin dependent diabetes millitus ( NIDDM )
Novaes et al., Braz Dent J 1997 (Dental Plaque...) : The periodontal condition of 30 type II non-insulin dependent diabetic patients ( NIDDM ) was evaluated and compared to that of 30 non-diabetic patients ( age range, 30-77 years )
Diraison et al., Diabetologia 1998 (Diabetes Mellitus, Type 2) : To test whether gluconeogenesis is increased in non-insulin dependent diabetic ( NIDDM ) patients we infused ( post-absorptive state ) healthy subjects and NIDDM patients with [ 6,6-2H2 ] glucose ( 150 min ) and [ 3-13C ] lactate ( 6 h )
Fioretto et al., Diabetologia 1998 (Albuminuria...) : In contrast MA does not reflect microvascular damage in a substantial number of non-insulin dependent diabetic ( NIDDM ) patients
Huang et al., Hum Genet 1998 (Diabetes Mellitus, Type 2...) : Therefore, we studied the association of the ACE gene I/D polymorphism with glucose intolerance and insulin resistance, and the contribution of this locus to genetic susceptibility to hypertension in non-insulin dependent diabetic mellitus ( NIDDM )
Azen et al., Control Clin Trials 1998 (Carotid Stenosis...) : The primary aim of the TRIPOD trial is to test the hypothesis that chronic administration of troglitazone to nondiabetic women with prior gestational diabetes mellitus ( GDM ) will improve whole-body insulin sensitivity and reduce the incidence of non-insulin dependent diabetes ( NIDDM )
Day et al., Diabetologia 1998 (Diabetes Mellitus, Type 2...) : Insulin resistance is a feature of non-diabetic relatives of non-insulin dependent diabetic ( NIDDM ) families
Sjöberg et al., J Intern Med 1998 (Celiac Disease...) : A series comprising 1664 diabetes patients [ 848 with IDDM, 745 with non-insulin dependent diabetes ( NIDDM ) and 71 with secondary diabetes ] were screened for GA. IgA- or IgG-GA positive sera were analysed for EMA
Lee et al., Mol Cell Biol 1998 (Diabetes Mellitus, Type 2...) : Both dwarfism and NIDDM are most likely due to the loss of expression of insulin-like growth factor I (IGF-I) and lower levels of insulin , resulting in stunted growth and elevated serum glucose levels, respectively
Murakami et al., Artery 1997 (Diabetes Mellitus, Type 2...) : Plasma lipoproteins and clinical characteristics of non-insulin dependent diabetic mellitus ( NIDDM ) patients with ( n = 50 ) and without ( n = 108 ) ischemic heart disease ( IHD ) were compared
Altobelli et al., Epidemiol Prev 1998 (Diabetes Mellitus, Type 1) : The family history data collection for IDDM and non insulin dependent diabetes ( NIDDM ) were obtained by a questionnaire, administered to parents
Chico et al., Diabetologia 1998 (Albuminuria...) : Fasting homocysteine concentrations were measured in the plasma of 165 diabetic patients ( 75 with insulin dependent [ IDDM ] ; 90 with non-insulin dependent diabetes [ NIDDM ] ) and 56 non-diabetic control subjects
Mandić et al., Biochem Mol Biol Int 1998 (Diabetes Mellitus, Type 1...) : The activity of the isoenzymes of N-acetyl-beta-D-glucosaminidase ( NAG, EC 3.2.1.30 ) is determined in the serum of insulin dependent ( IDDM ) and non-insulin dependent diabetics ( NIDDM ) with or without diabetic complications
Robertson et al., Diabetes Res Clin Pract 1998 (Birth Weight...) : Evidence is accumulating to suggest that the intrauterine environment may not only influence fetal growth and anthropometric indices at birth but also contribute to susceptibility to adult onset diseases such as non-insulin dependent diabetes ( NIDDM )
Shiba et al., Metabolism 1998 (Body Weight...) : To investigate the time course of the hepatic glucose metabolism in non-insulin dependent diabetes ( NIDDM ), we measured hepatic glucose production ( HGP ) and first-pass uptake of portal glucose infusion by the liver ( HGU ) using dual-tracer methods in a NIDDM model, Otsuka Long-Evans Tokushima Fatty ( OLETF ) rats, and in normal controls, Long-Evans Tokushima Otsuka ( LETO ) rats, at 8, 14, and 28 weeks of age ( n = 5, respectively )
Gimeno et al., Rev Saude Publica 1998 (Diabetes Mellitus, Type 2...) : At that time, 91 ( 17 % ) were classified as non-insulin dependent diabetic subjects ( NIDDM ), 90 ( 17 % ) with impaired glucose tolerance ( IGT ) and 349 ( 66 % ) as normal, according to WHO criteria
De Mattia et al., Am J Hypertens 1998 (Albuminuria...) : To evaluate the role of circulating and renal endothelin-1 (ET-1) in early diabetic nephropathy, plasma ET-1 levels and urinary ET-1 excretion were evaluated in lean, normotensive patients affected by non-insulin dependent diabetes ( NIDDM ) either with ( n = 9, NIDDM+ ) or without microalbuminuria ( n = 18, NIDDM- ) ; in never treated, lean, essential hypertensive patients with ( n = 12, EH+ ) or without microalbuminuria ( n = 10, EH- ) ; and in healthy volunteers ( n = 12 )
Jansson et al., Eur J Clin Invest 1998 (Diabetes Mellitus, Type 2...) : The subjects were divided into four different groups : ( a ) young lean control subjects [ age 31 +/- 1 years, mean +/- SE, BMI ( body mass index ) 22.7 +/- 0.4 kg m-2 ] ; ( b ) young obese subjects ( age 29 +/- 2 years, BMI 37.8 +/- 1.8 kg m-2 ) ; ( c ) middle aged obese subjects ( age 50 +/- 2 years, BMI 30.2 +/- 0.9 kg m-2 ) ; and ( d ) middle aged obese non-insulin dependent diabetic ( NIDDM ) subjects ( age 54 +/- 2 years, BMI 30.0 +/- 0.7 kg m-2 )
Vilbergsson et al., J Intern Med 1998 (Coronary Disease...) : The main aim of this study was to estimate the independent risk for coronary heart disease (CHD) death associated with non-insulin dependent ( Type 2 ) diabetes ( NIDDM ) and effect on life expectancy
Watts et al., Atherosclerosis 1998 (Diabetes Mellitus, Type 1...) : Endothelial dysfunction in non-insulin dependent ( Type 2 ) diabetes mellitus ( NIDDM ) has implications for the pathogenesis of the two major complications, macrovascular disease and microangiopathy
Hänninen et al., Diabetes Res Clin Pract 1998 (Coronary Disease...) : The health related quality of life ( HRQOL ) was studied in non-insulin dependent diabetic ( NIDDM ) patients aged under 65 years, compared with age- and gender matched controls, with the Medical Outcomes Study short-form ( SF-20 ) general measure
Hong et al., Scand J Prim Health Care 1998 (Diabetes Mellitus, Type 2...) : 55 patients with non-insulin dependent diabetes ( NIDDM ) aged 35-84 years ( 51 % males ), and 53 non-diabetic controls matched for age ( +/- 5 years ) and gender
Turner et al., Fortschr Arzneimittelforsch 1998 (Diabetes Mellitus, Type 2...) : Impaired glucose tolerance and non-insulin dependent diabetes ( NIDDM ) are the pathologic consequence of two co-incident and interacting conditions, namely insulin resistance and relative insulin deficiency