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CASP14 — NOD1

Text-mined interactions from Literome

Yoo et al., Biochem Biophys Res Commun 2002 : Because Nod1 also binds to RIP2, we hypothesized that Nod1 plays a role in pro-caspase-1 activation and IL-1beta processing ... Nod1 enhances pro-caspase-1 oligomerization and pro-caspase-1 processing
Rogler et al., Curr Opin Gastroenterol 2004 : Important new insights have been gained into the function of caspase activating and recruitment domain-15 ( CARD15 ) /NOD2 , the first cloned susceptibility gene for Crohn disease ( CD )
da Silva Correia et al., Cell Death Differ 2007 (Breast Neoplasms) : In contrast, several lines of evidence show that Nod1 dependent JNK activation and IL-8 production did not require the presence of caspase 8 but required activation of TAK1 as well as RIP2
Warren et al., J Immunol 2008 (Listeriosis) : Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection ... We demonstrate that the presence of L. monocytogenes within the cytosolic compartment induces caspase 1 activation through multiple Nod-like receptors, including Ipaf and Nalp3
Miao et al., J Clin Immunol 2010 : This proteolysis is dependent upon caspase 1, which is activated by Nod-like receptor ( NLR ) signaling
Saïd-Sadier et al., Biomed J 2012 (Inflammation) : Recent research has revealed that DAMPs and PAMPs synergize to permit secretion of pro-inflammatory cytokines such as interleukin-1ß (IL-1ß) : PAMPs stimulate synthesis of pro-IL-1ß, but not its secretion ; while DAMPs can stimulate assembly of an inflammasome containing, usually, a Nod-like receptor ( NLR ) member, and activation of the protease caspase-1 , which cleaves pro-IL-1ß into IL-1ß, allowing its secretion