◀ Back to NOX3
NOX1 — NOX3
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Sorescu et al., Circ Res 2004
:
Together, these results suggest that BMP4 produced in ECs by OS stimulates ROS release from the
nox1 dependent
NADPH oxidase leading to inflammation, a critical early atherogenic step
Valente et al., Free Radic Biol Med 2007
:
NOX1 NADPH oxidase regulation by the NOXA1 SH3 domain
Choi et al., J Biol Chem 2008
:
Ang II enhanced the activity of both
Nox1 and Nox2 supported by either adaptor pair, with more effective activation of Nox1 in the
presence of NOXO1 and NOXA1 and of
Nox2 in the presence of p47(phox) and p67(phox)
Chose et al., J Cardiovasc Pharmacol 2008
:
Distinct
role of
nox1 , nox2, and p47phox in unstimulated versus angiotensin II-induced
NADPH oxidase activity in human venous smooth muscle cells
Dammanahalli et al., Endocrinology 2008
:
ET1 significantly attenuated NADPH oxidase activity and cell proliferation, which could be abolished by silence of Nox1 gene, suggesting that ET1 induced inhibition of
NADPH oxidase activity was
mediated by
Nox1
Chéret et al., J Neurosci 2008
(Encephalitis...) :
Neurotoxic activation of microglia is promoted by a
nox1 dependent
NADPH oxidase
Aoyama et al., Hepatology 2012
(Liver Cirrhosis) :
The
NOX1/4 inhibitor, GKT137831,
attenuated liver fibrosis and ROS production in both SOD1mu and WT mice as well as messenger RNA expression of fibrotic and
NOX genes
Weaver et al., Mol Cell Endocrinol 2013
:
Inhibition of
NADPH oxidase activity
blocked stimulated
NOX-1 expression ( p < 0.05 )