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CREB5 — NTRK2

Text-mined interactions from Literome

Pizzorusso et al., J Neurosci 2000 : CREB phosphorylation required trkB activation because treatment with the trk inhibitor k252a completely blocked CREB phosphorylation
Soto et al., J Neurochem 2006 : Our results suggest that FGF-2 acts on RGCs via FGFR1, activating the ERK pathway and CREB to increase BDNF synthesis, and PKA and CREB to increase TrkB synthesis
Kingsbury et al., Mol Cell Neurosci 2007 : Here we identify a novel regulatory element designated TCaRE3 ( TRKB Ca ( 2+ ) response element 3 ) required for CREB dependent TRKB transcription in neurons ... Mutation analysis of the human TRKB promoter region demonstrated that the role of TCaRE3 is also conserved, suggesting that the functional interaction between CREB bound to the CREs and KLF7 bound to TCaRE3 is essential for the proper regulation of TRKB in neurons
Sánchez-Huertas et al., Cereb Cortex 2011 : CREB-Dependent Regulation of GAD65 Transcription by BDNF/TrkB in Cortical Interneurons ... Dissection of the intracellular pathway that underlies this process revealed that BDNF/TrkB signaling controls the transcription of GAD65 in a Ras-ERK-CREB dependent manner
Duman et al., J ECT 1998 : Studies in vivo and in cultured cells indicate that the induction of BDNF and TrkB is mediated by the cyclic adenosine monophosphate ( cAMP ) response element binding protein ( CREB ), a transcription factor that is activated by cAMP and Ca2+ intracellular pathways