UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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NUP214 — SMAD7

Pathways - manually collected, often from reviews:

NCI Pathway Database BMP receptor signaling: SMAD6-7/SMURF1/SMAD1 complex (SMAD6_SMAD7-SMURF1-SMAD1) → NUP214 (NUP214) (translocation, inhibits) Sapkota et al., Mol Cell 2007, Hoodless et al., Cell 1996, Kretzschmar et al., Genes Dev 1997
Evidence: mutant phenotype, assay