Gene interactions and pathways from curated databases and text-mining

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IL4 — PAF1

Text-mined interactions from Literome

Bastien et al., J Immunol 1999 : PAF induced IL-4 and IL-13 mRNA expression in 17 % of CD20+ cells, and IL-4 was detected in cell supernatants after 48-72 h of culture
Wierzbicki et al., J Leukoc Biol 2003 : IL-4 alone did not enhance PAF synthesis or PGE ( 2 ) release ; however, pretreatment with IL-4 primed for PAF synthesis and PGE ( 2 ) release in response to subsequent stimulation with histamine
Kushikata et al., Neurosci Lett 2006 (Fever) : PAF and its receptor are found in brain and PAF affects or is affected by the production of sleep promoting cytokines such as interleukin-1
Wang et al., Mediators Inflamm 1996 : Our previous studies have shown that EsA could reduce the release of platelet activating factor (PAF) from rat macrophages, and inhibit interleukin-1 and interleukin-6 production from routine macrophages
Bussolino et al., Biochim Biophys Acta 1987 : These findings indicate that interleukin 1 induces the PAF synthesis by a deacylation/reacetylation mechanism into human endothelial cells