Gene interactions and pathways from curated databases and text-mining

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IL8 — PAK3

Text-mined interactions from Literome

Tseng et al., Am J Physiol Cell Physiol 2006 (Inflammation) : Apical Pseudomonas aeruginosa strain PAK ( but not flagellin mutant PAK.fliC ), flagellin, and flagellin + PAK.fliC activated NF-kappaB and IL-8 expression and secretion
Park et al., Am J Physiol Lung Cell Mol Physiol 2012 : These combined data are consistent with the hypothesis that PPAR? stimulates MUC1/Muc1 expression, thereby blocking PMA/PAK induced TNF-a/IL-8 production by airway epithelial cells