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CA2 — PDHX

Text-mined interactions from Literome

Czerniecki et al., J Nutr Sci Vitaminol (Tokyo) 2001 : The role of Mg2+, Ca2+ , and Mn2+ in regulation of purified pig heart pyruvate dehydrogenase complex (PDC) containing endogenous thiamin diphosphate ( TDP ) was studied
Spriet et al., Exerc Sport Sci Rev 2002 : During exercise, pyruvate dehydrogenase activation in human skeletal muscle is proportional to the relative aerobic power output ( percent VO2max ) and is regulated by increases in Ca2+ , free ADP, and pyruvate concentrations
Boja et al., J Proteome Res 2009 : As a reference reaction, we monitored the well characterized regulation of pyruvate dehydrogenase (PDH) activity via phosphorylation/dephosphorylation by pyruvate dehydrogenase kinase/pyruvate dehydrogenase phosphatase in response to dichloroacetate, de-energization and Ca2+
Macdonald et al., Horm Metab Res 1978 : Regulation of pyruvate dehydrogenase by Ca2+ , 3'5 ' cyclic AMP and adrenalin in isolated rat kidney tubules
McCormack et al., Biochem J 1990 : 5. Increasing extracellular Ca2+ or adding uncoupler also activated pyruvate dehydrogenase to a similar degree, but only the former was associated with increased insulin secretion
Vlessis et al., J Neurochem 1990 (Brain Ischemia) : Respiratory inhibition induced by Ca2+ and tBOOH does not involve pyruvate dehydrogenase (PDH) inhibition since PDH flux increased linearly with tBOOH concentration ( R = 0.96 )
Hansford et al., Biochim Biophys Acta 1990 : ( 4 ) These results are consistent with a role of mitochondrial Ca2+ in activating pyruvate dehydrogenase in the intact heart
Rutter et al., Biochim Biophys Acta 1989 : Regulation of the pyruvate dehydrogenase complex by Ca2+ within toluene permeabilized heart mitochondria ... ( 1 ) Rat heart mitochondria, permeabilized to all low Mr solutes by toluene treatment, have been used to study the regulation in situ of the phosphatase and kinase components of the pyruvate dehydrogenase complex (PDH) by Ca2+
Denton et al., Biochem J 1980 : Effects of Na+, Mg2+ and ruthenium red on the Ca2+ stimulated oxidation of oxoglutarate and on pyruvate dehydrogenase activity in intact rat heart mitochondria
Baumgarten et al., Biochem J 1983 : Digitonin permeabilized cells required 0.5 microM free Ca2+ for half-maximal activation of pyruvate dehydrogenase
Bünger et al., Am J Physiol 1984 : Parallel stimulation by Ca2+ of inotropism and pyruvate dehydrogenase in perfused heart
Oviasu et al., Biochem J 1984 (Starvation) : The effects of these hormones on pyruvate dehydrogenase activity were critically dependent on extracellular Ca2+ , thus suggesting a role for this ion in the mechanism of action of the hormones
McCormack et al., Biochem J 1980 : 3. Overall, the results of this study demonstrate that the activities of pyruvate dehydrogenase , NAD+-isocitrate dehydrogenase and oxoglutarate dehydrogenase may all be increased by Ca2+ and Sr2+ within intact mitochondria
Civelek et al., Biochem J 1996 (Insulinoma...) : Respiration from pyruvate was high and not influenced by Ca2+ in State 3 or under various redox states and fixed values of the ATP/ADP ratio ; nevertheless, high Ca2+ elevated pyridine nucleotide fluorescence, indicating activation of pyruvate dehydrogenase by Ca2+