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PDLIM7 — SMAD6
Text-mined interactions from Literome
Prokova et al., J Biol Chem 2002
(Cell Transformation, Neoplastic) :
LMP1 strongly
inhibited the uninduced and the
Smad-inducible activity of the promoters of the human p21/WAF1/Cip1 gene and the mouse Smad7 gene ... Inhibition of TGFbeta signaling and
Smad dependent activation of transcription by
LMP1 was greatly reduced by deletion of both C-terminal activating regions 1 and 2 of LMP1 as well as by overexpression of a non-degradable form of IkappaB
Tzimas et al., Cell Signal 2006
:
Overexpression of USP31 in HEK 293T cells inhibited TNFalpha, CD40,
LMP1 , TRAF2, TRAF6 and IKKbeta mediated NF-kappaB activation, but did not
inhibit Smad mediated transcription activation