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NOX3 — PI3

Text-mined interactions from Literome

Yasui et al., Cell Biochem Funct 2001 : NADPH oxidase is activated in a PI3-kinase dependent manner at the early phase, and PLD activity follows it and is related to superoxide production at the late phase in human neutrophils by stimulation with FMLP
Alblas et al., Mol Cell Biol 2005 : Furthermore, SIRPalpha induced NO production required the generation of hydrogen peroxide ( H ( 2 ) O ( 2 ) ) by a NADPH oxidase ( NOX ) and the phosphatidylinositol 3-kinase (PI3-K) dependent activation of Rac1, an intrinsic NOX component
Hawkins et al., Biochem Soc Symp 2007 : The role of PI3Ks in the regulation of the neutrophil NADPH oxidase
Zhang et al., Antioxid Redox Signal 2008 (Lung Diseases) : Here we evaluated the role of PI-3-kinase and rac in activation of endothelial NADPH oxidase ... These results indicate that PI-3-kinase and the small G protein rac are involved in the activation of endothelial cell NADPH oxidase that is associated with the acute loss of shear stress
Anderson et al., Blood 2008 : CD18 dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks
Harada et al., Biol Pharm Bull 2012 (Legionnaires' Disease) : Class I phosphatidylinositol 3-kinase (PI3-K) and its product phosphatidylinositol 3,4,5-trisphosphate ( PI ( 3,4,5 ) P3 ) play key roles in the reorganization of cytoskeleton ( phagocytosis ) and activation of nicotinamide adenine dinucleotide phosphate ( NADPH ) oxidase ( ROS production )