UCSC Genome Browser Gene Interaction Graph

We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

Gene interactions and pathways from curated databases and text-mining

◀ Back to RAC3

PIK3CG — RAC3

Pathways - manually collected, often from reviews:

KEGG VEGF signaling pathway: PIK3CA/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIK3R5 → RAC1/RAC2/RAC3 (protein-protein, compound)
KEGG Natural killer cell mediated cytotoxicity: PIK3CA/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIK3R5 → RAC1/RAC2/RAC3 (protein-protein, activation)
KEGG Fc epsilon RI signaling pathway: PIK3CA/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIK3R5 → RAC1/RAC2/RAC3 (protein-protein, activation)

Text-mined interactions from Literome

Vecchione et al., J Exp Med 2005 (Hypertension) : In response to angiotensin II, PI3Kgamma was required for the activation of Rac and the subsequent triggering of ROS production
Welch et al., Curr Biol 2005 : Deficiency in PI3Kgamma , an upstream regulator of Rac , causes a similar phenotype