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MOK — PIM1
Text-mined interactions from Literome
Meloche et al., Arterioscler Thromb Vasc Biol 2011
:
Therefore, we hypothesized that
RAGE/STAT3 activation in VSMC
activates Pim1 , promoting NFAT and thus VSMC proliferation and resistance to apoptosis
Zeng et al., FASEB J 2012
:
RAGE opposes Myd88 signaling at multiple levels : by suppression of p65 levels, thereby reducing activation of NF-?B and consequent production of cyclin D1, and by suppression of Il6 mediated phosphorylation of Stat3, thereby down
regulating Pim1 and suppressing the hyperplastic response