Gene interactions and pathways from curated databases and text-mining

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EGFR — PLA2G4A

Text-mined interactions from Literome

Chang et al., Toxicology 2011 : Involvement of the epidermal growth factor receptor in Pb²+ induced activation of cPLA2/COX-2 genes and PGE2 production in vascular smooth muscle cells ... Furthermore, Pb²+ induced activation of the COX-2/cPLA2 genes was inhibited by both epidermal growth factor receptor (EGFR) inhibitors ( AG1478 and PD153035 ) and EGFR siRNA
Li et al., J Hepatol 2011 (Drug-Induced Liver Injury) : Hepatic overexpression of cPLA(2)a increases the expression of EGFR in the liver and the EGFR inhibitor, AG1478, exacerbated Jo2 mediated liver injury