Gene interactions and pathways from curated databases and text-mining

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FGF10 — PLAU

Text-mined interactions from Literome

Green et al., Photochem Photobiol 2001 : Basic fibroblast growth factor , a heparin binding growth factor known to be UVR-inducible in mesenchymal cells, stimulated uPA production and cell proliferation ; however, anti-bFGF antibodies did not significantly decrease proliferation or basal uPA production
Sieuwerts et al., Thromb Haemost 2002 (Breast Neoplasms...) : mRNA analysis revealed that FGF-1, FGF-2 and FGF-4 induced the mRNA expression levels of uPA , tPA, uPAR, PAI-1 and PAI-2, and reduced those of IGF-1, IGF-1R, IGF-2R and IGFBP-4, without significantly affecting the levels of IGFBP-3, IGFBP-5 and IGFBP-6 mRNA
Mochizuki et al., Oncogene 2002 : In cells stably expressing mutant p85alpha subunit, FGF-2 efficiently induced uPA production
Rogister et al., Glia 1990 (Adrenal Gland Neoplasms...) : We have previously shown that the proliferation of cultured astrocytes can be stimulated by the urokinase-type ( uPA ) of plasminogen activator (PA) and that astrocytes are able to release such uPA upon stimulation with basic fibroblast growth factor , which is known to act as a mitogen for these cells