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PLCG1 — PLD2
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Bind Interaction:
PLCG1
—
PLD2
Lee et al., J Biol Chem 2004*
-
IRef Bind_translation Interaction:
PLCG1
—
PLD2
(affinity chromatography technology)
Lee et al., J Biol Chem 2004*
-
IRef Biogrid Interaction:
PLCG1
—
PLD2
(physical association, affinity chromatography technology)
Jang et al., J Biol Chem 2003*
-
IRef Biogrid Interaction:
PLCG1
—
PLD2
(direct interaction, pull down)
Jang et al., J Biol Chem 2003*
-
IRef Hprd Interaction:
PLCG1
—
PLD2
(in vivo)
Jang et al., J Biol Chem 2003*
-
IRef Hprd Interaction:
PLCG1
—
PLD2
(in vitro)
Jang et al., J Biol Chem 2003*
-
IRef Ophid Interaction:
PLCG1
—
PLD2
(aggregation, confirmational text mining)
Jang et al., J Biol Chem 2003*
-
IRef Ophid Interaction:
PLCG1
—
PLD2
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Slaaby et al., Biochem J 2000
:
Insulin induced
phospholipase D1 and phospholipase D2 activity in human embryonic kidney-293 cells
mediated by the
phospholipase C gamma and protein kinase C alpha signalling cascade ... Insulin induced phospholipase D1 and
phospholipase D2 activity in human embryonic kidney-293 cells
mediated by the
phospholipase C gamma and protein kinase C alpha signalling cascade
Jang et al., J Biol Chem 2003
:
However, neither
PLD2 wild type nor PLD2 mutant
affects the EGF induced tyrosine phosphorylation of
PLC-gamma1
Lee et al., J Biol Chem 1994
:
Activation of
phospholipase D induced by platelet derived growth factor is
dependent upon the level of
phospholipase C-gamma 1 ... PDGF stimulated PLD activation was 10-fold greater in 3T3-gamma 1 cells than in 3T3-C cells, indicating that
PLD activation is
dependent upon the level of
PLC-gamma 1 ... Therefore, these results suggest that PDGF induced
PLD activation may be a
consequence of primary stimulation of
PLC-gamma 1 and that PLD may play a role downstream from PLC-gamma 1 in PDGF triggered mitogenesis
Yeo et al., J Biol Chem 1994
:
Activation of
phospholipase C-gamma is
necessary for stimulation of
phospholipase D by platelet derived growth factor ... In summary, these results indicate that activation of
PLC gamma 1 and protein kinase C are
necessary for the stimulation of
PLD by PDGF and provide no evidence for alternative mechanisms