Gene interactions and pathways from curated databases and text-mining

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NOTCH1 — POGLUT1

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Ma et al., Biochem Biophys Res Commun 2011 (Leukemia) : We showed that lack of hCLP46 results in impaired ligand induced Notch activation in mammalian cell, and hCLP46 regulates the proliferation of U937 cell through CDKI-RB signaling pathway, which may be important for the pathogenesis of leukemia
Chu et al., Cell Prolif 2013 (Precursor Cell Lymphoblastic Leukemia-Lymphoma) : Overexpression of hCLP46 enhances Notch activation and regulates cell proliferation in a cell type dependent manner ... hCLP46 overexpression enhanced Notch1 activation in 293Trex cells in a ligand dependent manner, with increased Notch signalling enhancing Hes1 expression