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NOTCH1 — POGLUT1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Ma et al., Biochem Biophys Res Commun 2011
(Leukemia) :
We showed that lack of
hCLP46 results in impaired ligand
induced Notch activation in mammalian cell, and hCLP46 regulates the proliferation of U937 cell through CDKI-RB signaling pathway, which may be important for the pathogenesis of leukemia
Chu et al., Cell Prolif 2013
(Precursor Cell Lymphoblastic Leukemia-Lymphoma) :
Overexpression of
hCLP46 enhances
Notch activation and regulates cell proliferation in a cell type dependent manner ...
hCLP46 overexpression
enhanced Notch1 activation in 293Trex cells in a ligand dependent manner, with increased Notch signalling enhancing Hes1 expression