Gene interactions and pathways from curated databases and text-mining

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CASP4 — PPP1R3A

Text-mined interactions from Literome

Wei et al., Neurosci Lett 2008 : This study demonstrated that Rg1 can reduce the production of Abeta ( 1-42 ) and the activation of caspase-3 , as a result, to attenuate the cell apoptosis
Li et al., Zhongguo Zhong Yao Za Zhi 2010 (Alzheimer Disease...) : And the effects of ginsenoside Rg1 on the expressions of P-Tau and caspase-3 in brain slices from AD model rats in each group were observed with immunohistochemistry and image analysis technology ... Ginsenoside Rg1 could inhibit the expression of P-Tau to slow the formation of neurofibrillary tangles and could inhibit the expression of caspase-3 to inhibit neuronal apoptosis to protect the nerve cells, so as to play the role of anti-dementia