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IL5 — PRDM1
Text-mined interactions from Literome
Yasue et al., Int Immunol 1999
:
Furthermore, stimulation of splenic B cells with
IL-5 together with CS/2
induces Blimp-1 expression and differentiation into Ig-producing cells
Tsukamoto et al., Biochem Biophys Res Commun 2005
:
IL-5 induces AID and
Blimp-1 expression in CD38- and CD40 activated B-2 cells, leading to mu to gamma1 CSR at DNA level and IgG1 production
Takatsu et al., Adv Immunol 2009
(Hypersensitivity) :
IL-5 critically regulates homeostatic proliferation and survival of and natural antibody production by B-1 cells, and
enhances the AID and
Blimp-1 expression in activated B-2 cells leading to induce mu to gamma1 class switch recombination and terminal differentiation to IgM- and IgG1 secreting plasma cells, respectively