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CDKN1A — PRL
Text-mined interactions from Literome
Wu et al., Cancer Res 2005
(MAP Kinase Signaling System...) :
S179D
prolactin increases vitamin D receptor and
p21 through up-regulation of short 1b prolactin receptor in human prostate cancer cells ... Blockade of ERK signaling eliminated S179D
PRL stimulated expression of the VDR and
p21 in LnCAP cells and transfected PC3 and DU145 cells
Wu et al., Oncol Res 2006
:
S179D
PRL , by contrast, had no effect on cyclin D1 and cdk4 expression, but
increased p21 expression and expression of the vitamin D receptor (VDR)