Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
VEGFA
→
PTGER2
(increases, VEGFA Activity)
Evidence: in both benign and malignant mouse intestinal tumors, stromal expression of COX2 results in elevated PGE2 levels that stimulate, in turn, cell surface receptor EP2, followed by induction of VEGF and angiogenesis