Gene interactions and pathways from curated databases and text-mining

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CCL2 — PTH

Text-mined interactions from Literome

Sukumar et al., J Clin Endocrinol Metab 2011 (Obesity) : Because both PTH and MCP-1 levels are higher in obesity, the goal was to determine whether the high MCP-1 occurs only in the presence of high serum PTH and is independent of adiposity and examine its relationship with bone mineral density ( BMD ) and turnover ... Together these data suggest that MCP-1 is higher only in the presence of increased PTH and that adiposity alone can not explain the higher MCP-1 levels in obesity
Zhu et al., J Bone Miner Res 1994 : The effects of interleukin-1 beta (IL-1 beta), tumor necrosis factor alpha (TNF-alpha), interleukin-6 (IL-6), transforming growth factor beta ( TGF-beta ), platelet derived growth factor ( PDGF-BB ), parathyroid hormone (PTH) , and 1,25 ( OH ) 2D3 on MCP-1 expression in human osteoblastic cells were compared ... The osteotrophic mediators PTH and 1,25 ( OH ) 2D3 and PDGF-BB had no effect on MCP-1 expression