Armbrecht et al., Arch Biochem Biophys 2003
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PTH and forskolin stimulated CYP1alpha promoter activity via a cAMP dependent pathway acting through the phosphorylation of CREB ( cAMP dependent response element binding protein )
Armbrecht et al., J Steroid Biochem Mol Biol 2007
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To study these possibilities, we examined the effect of PTH and free radicals on CYP1alpha expression in a model system-AOK-B50 renal tubular cells ... H ( 2 ) O ( 2 ) inhibited PTH stimulated CYP1alpha protein levels and 1,25 ( OH ) ( 2 ) D production in a dose dependent manner