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JAK2 — PTK7

Text-mined interactions from Literome

Yu et al., J Biol Chem 2003 : IL-6 increased phosphorylation of STAT3 ( at Tyr ( 705 ) ) and ERK1/2 ( at Tyr ( 204 ) ) within 5 min that peaked at 15-30 min and returned to basal levels at 2 h. Phosphorylation of STAT3 was blocked by genistein, a protein tyrosine kinase inhibitor, and AG490, a JAK2 inhibitor , but not PD98059, an ERK1/2 kinase inhibitor
Xenaki et al., Cell Signal 2004 : Activation of Bcr-Abl PTK does not phosphorylate or activate either ERK-1/2 or JAK-2/STAT-5b , suggesting that these signal transduction pathways are not involved in Abl PTK mediated suppression of apoptosis in FDCP-Mix cells