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RAC2 — RAD50

Text-mined interactions from Literome

Maillet et al., Nat Cell Biol 2003 (Alzheimer Disease) : We also show that Rac activation results from activation of Rap1 through the cAMP guanine nucleotide-exchange factor (GEF) Epac1
Sato et al., Cancer Sci 2005 : The activation of Cdc42 and Rac by the trans-interaction of nectin and nectin is mediated by c-Src, another small G protein, Rap1 , a Cdc42-GEF, FRG, and a Rac-GEF, Vav2 ... The trans-interaction of Necl-5 and nectin-3 also activates Rap1 through C3G, a Rap-GEF, and this activation of Rap1 is required for the activation of Cdc42 and Rac
Birukova et al., Exp Cell Res 2007 (Respiratory Distress Syndrome, Adult) : Prostaglandins PGE ( 2 ) and PGI ( 2 ) promote endothelial barrier enhancement via PKA- and Epac1/Rap1 dependent Rac activation