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BRCA1 — RBL1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Fan et al., Oncogene 2001
:
Over-expression of wild-type
BRCA1 ( wtBRCA1 ) did not cause cell cycle arrest but did
cause down-regulation of expression of RB,
p107 , p130, and other proteins ( e.g., p300 ), associated with increased sensitivity to DNA damaging agents
Bindra et al., Cancer Biol Ther 2006
(Breast Neoplasms...) :
In contrast to previous studies, we have also detected promoter occupancy by the pocket proteins p130 and p107, but not Rb, our data indicate that E2F4 and
p130/p107 complexes basally
repress the
BRCA1 promoter