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HDAC1 — RECK
Text-mined interactions from Literome
Liu et al., Cancer Res 2003
(Lung Neoplasms...) :
In this study, we test the possibility that
HDAC inhibitor may
increase RECK expression to inhibit MMP activation and cancer cell invasion
Lee et al., Biochim Biophys Acta 2010
(Anoxia) :
Hypoxia induced downregulation of RECK was abolished by knockdown of HDAC1 and HIF-1alpha with respective small interfering RNAs ( siRNAs ), whereas overexpression of
HDAC1 and HIF-1alpha
suppressed RECK expression similar to the level under hypoxic conditions
Jeon et al., Mol Cancer Ther 2010
(Neoplasm Invasiveness...) :
In conclusion, the inhibition of
HDAC successfully
restored the expression of
RECK under hypoxic conditions