Gene interactions and pathways from curated databases and text-mining

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MAPK15 — RIT1

Text-mined interactions from Literome

Sakabe et al., FEBS Lett 2002 (Cell Transformation, Neoplastic...) : Rit exhibits a distinct C-terminus and effector domain, and does not activate mitogen activated protein kinase ( MAPK ) but can cooperate with Raf to transform fibroblasts
Andres et al., J Neurochem 2008 : Silencing of Rit by RNA interference suppressed IFNgamma elicited activation of p38 MAPK in pheochromacytoma cells, and pharmacological inhibition of p38 MAPK significantly attenuated the dendrite inhibiting effects of IFNgamma in cultured sympathetic and hippocampal neurons without altering signal transducer and activator of transcription 1 activation