Gene interactions and pathways from curated databases and text-mining

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IL21 — RPL17

Text-mined interactions from Literome

Ma et al., Immunology 2011 (Hepatitis C, Chronic) : PD-1 negatively regulates interleukin-12 expression by limiting STAT-1 phosphorylation in monocytes/macrophages during chronic hepatitis C virus infection
Cubas et al., Nat Med 2013 (HIV Infections...) : In fact, we show that engagement of PD-1 on TFH cells leads to a reduction in cell proliferation, activation, inducible T-cell co-stimulator (ICOS) expression and interleukin-21 (IL-21) cytokine secretion