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NGF — RRAS

Text-mined interactions from Literome

Kimmelman et al., Mol Cell Biol 2002 : We found that R-Ras3 was activated by nerve growth factor (NGF) and basic fibroblast growth factor as well as by the guanine nucleotide exchange factor GRP but not by epidermal growth factor
Iwashita et al., J Biol Chem 2007 (Hemorrhage...) : We found that R-Ras GAP is down-regulated during neurite formation in rat pheochromocytoma PC12 cells by nerve growth factor (NGF) , which is blocked by the transient expression of R-Ras gap or dominant negative R-ras cDNA ... By establishing a PC12 subclone that stably expresses exogenous R-Ras GAP, it was found that NGF reduced endogenous R-Ras GAP but not exogenous R-Ras GAP, suggesting that down-regulation of R-Ras GAP occurs at the transcription level