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MMP19 — SAA1

Text-mined interactions from Literome

Connolly et al., Arthritis Rheum 2012 (Arthritis, Rheumatoid...) : The effects of A-SAA on MMP/TIMP expression on RA fibroblast-like synoviocytes ( FLS ), primary human chondrocytes, and RA/psoriatic arthritis synovial explant cultures were assessed using real-time polymerase chain reaction, enzyme linked immunosorbent assay, antibody protein arrays, and gelatin zymography ... A-SAA increased MMP-1, MMP-3 , MMP-13, and MMP/TIMP expression in RA FLS and synovial explants ( P < 0.05 ) ... In chondrocytes, A-SAA induced MMP-1, MMP-3 , and MMP-13 messenger RNA and protein expression ( all P < 0.01 ), resulting in a significant shift in MMP : TIMP ratios ( P < 0.05 )
Migita et al., Lab Invest 1998 (Arthritis, Rheumatoid) : When SAA containing media were immunodepleted by anti-SAA-specific antibody, SAA mediated MMP secretion was also abrogated