Gene interactions and pathways from curated databases and text-mining

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CASP3 — SIVA1

Text-mined interactions from Literome

Resch et al., J Cell Sci 2009 : Ectopically expressed Siva1 increased caspase-3 activity, which was inhibited by XIAP in a ubiquitin-ligase dependent manner
Bhattacharya et al., Invest Ophthalmol Vis Sci 2011 : Knockdown of p53 decreased the basal expression of p21Cip1 and Bcl-2, inhibited the Nutlin-3 induced upregulation of Siva-1 and PUMA expression, and consequently inhibited caspase-3 activation