Gene interactions and pathways from curated databases and text-mining

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IRF6 — SLC27A5

Text-mined interactions from Literome

Shijubo et al., Eur Respir J 2000 (Sarcoidosis) : The inhibitory effects of recombinant CC10 on interferon gamma (IFN-gamma) production were examined using lipopolysaccharide (LPS) stimulated sarcoid BAL fluid cells, and the blocking effects of monoclonal antibody TY-5, directed against CC10, on CC10 function were also tested
Shigehara et al., J Immunol 2001 (Sarcoidosis, Pulmonary) : IL-18 mRNA expression was observed in freshly isolated sarcoid BAL fluid cells as well as in LPS stimulated sarcoid BAL fluid cells, but IFN-gamma and IL-12 mRNA expression was observed only in LPS stimulated BAL fluid cells ... Treatment with anti-IL-12- and anti-IL-18 neutralizing Abs significantly inhibited IFN-gamma production from LPS stimulated BAL fluid cells of sarcoid cases
Zhang et al., Shock 2002 (Pneumonia) : Intratracheal LPS induced a significant increase in MIP-2 in bronchoalveolar lavage (BAL) fluid with no detectable MIP-2 in the plasma
Takahashi et al., Sarcoidosis Vasc Diffuse Lung Dis 2004 (Inflammation...) : TAK-603 did not increase IL-10 or TGF-beta1 production in LPS stimulated BAL fluid cells of sarcoidosis patients
Moon et al., Respir Res 2009 (Acute Lung Injury...) : A pretreatment with RGDS inhibited LPS induced increases in neutrophil and macrophage numbers, total protein levels and TNF-alpha and MIP-2 levels, and matrix metalloproteinase-9 activity in bronchoalveolar lavage (BAL) fluid at 4 or 24 h post-LPS treatment
Turner et al., Circ Shock 1991 (Edema...) : Both 5LO inhibition and LTD4 receptor antagonism attenuated the LPS induced BAL erythrocyte increase