Gene interactions and pathways from curated databases and text-mining

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CASP1 — SMAD7

Text-mined interactions from Literome

Okado et al., Kidney Int 2002 : These data indicate that TGF-beta induced apoptosis in mesangial cells is mediated through the activation of caspase-3 by Smad7 , but not by Smad2 or Smad3
Yu et al., Biochem Biophys Res Commun 2005 (Colonic Neoplasms) : Smad7 overexpression also inhibited upregulation of p21 and caspase-3 activity by geinistein