Gene interactions and pathways from curated databases and text-mining

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SOCS1 — TCF4

Text-mined interactions from Literome

Hsu et al., Endocr Relat Cancer 2007 (Breast Neoplasms) : We also demonstrated that HER-2/neu increased beta-catenin/TCF mediated Jab1 expression via the AKT signaling pathway because chemical inhibitor or dominant negative mutant of AKT effectively attenuated the stimulatory action of HER-2/neu
Yang et al., J Cell Physiol 2011 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : Ectopic expression of dominant negative Tcf-4 mutant significantly attenuates Jab1 expression while over-expression of ß-catenin and STAT1 cooperatively up-regulates Jab1 promoter activity and mRNA expression