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MYO16 — SRC

Text-mined interactions from Literome

Fincham et al., EMBO J 2000 : Also, integrin engagement and v-Src induced myosin light chain kinase (MLCK) dependent phosphorylation of myosin light chain downstream of the MEK/ERK pathway, and MLCK and myosin activities are required for the focal adhesion targeting of ERK
Fincham et al., Mol Cell Biol 2000 : Here, we report that the SH3 domain is essential for the assembly of focal adhesions containing the oncoprotein by mediating a switch from a microtubule dependent, perinuclear localization to actin associated focal adhesions ; furthermore, v-Src translocation to focal adhesions requires myosin activity, at least under normal conditions when the actin cytoskeleton is being dynamically regulated