Henning et al., J Immunol 2008
:
SP-A decreases the phosphorylation of IkappaBalpha, a key regulator of NF-kappaB activity, and nuclear translocation of p65 which result in diminished TNF-alpha secretion in response to TLR ligands
Yoza et al., Cytokine 2011
(Sepsis) :
We further show TLR dependent NF?B p65 and histone H3 serine 10 phosphorylation binding at the promoter