Gene interactions and pathways from curated databases and text-mining

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TCF15 — TP53

Text-mined interactions from Literome

Webster et al., Mol Cell Biol 1999 : Here we show that both p53 and NF-kappaB inhibit each other 's ability to stimulate gene expression and that this process is controlled by the relative levels of each transcription factor
Yun et al., J Biol Chem 1999 : These results suggest that p53 negatively regulates cdc2 transcription and that the NF-Y transcription factor is required for the p53 mediated regulation
Rodriguez et al., J Virol 1999 : Previous studies showed that the EBV encoded immediate-early transcription factor , Zta, can induce expression of the cyclin dependent kinase inhibitors, p21 and p27, the tumor suppressor, p53 , and cell growth arrest
Lee et al., Oncogene 2000 (Carcinoma, Hepatocellular...) : p53mt249 stimulates transcription factor Sp1 phosphorylation which might be a cause of increased transcription factor binding on the P4 promoter while wild-type p53 does not
Budhram-Mahadeo et al., Neurosci Lett 2002 (Carcinoma, Squamous Cell...) : The Brn-3a POU family transcription factor stimulates p53 gene expression in human and mouse tumour cells
Wei et al., Cancer Res 2007 (Breast Neoplasms) : Previous work has shown that the Kruppel-like factor 4 (KLF4) transcription factor represses p53 transcription by binding to the PE21 element
Liu et al., Cell Death Differ 2007 : Here, we report that the human pituitary homeobox 1 ( hPitx1 ) transcription factor increases the expression of p53 at the mRNA and protein levels in human mammary carcinoma ( MCF-7 ) cells
Soto-Reyes et al., Oncogene 2010 (Cell Transformation, Neoplastic) : Epigenetic regulation of the human p53 gene promoter by the CTCF transcription factor in transformed cell lines
Sedaghat et al., PloS one 2012 (Neoplasms) : Wig-1 is a transcription factor regulated by p53 that can interact with hnRNP A2/B1, RNA Helicase A, and dsRNAs, which plays an important role in RNA and protein stabilization
Qiu et al., Curr Cancer Drug Targets 2012 (Carcinoma, Squamous Cell...) : The wide-type p53 induced gene 1 ( WIG-1 ) is a p53 regulated transcription factor
Hale et al., Nucleic Acids Res 1995 : We suggest that this novel transcription factor ( PF2 ) is critical for expression of the mouse p53 promoter