Ediger et al., Eur Respir J 2003
(Cell Transformation, Neoplastic...) :
Activation of the inhibitory guanine nucleotide binding protein and of ERK signalling pathways were required for most transcription factor responses to LPA Liliom et al., Biochim Biophys Acta 2006
(Calcium Signaling) :
The transcription factor peroxisome proliferator activated receptor gamma ( PPARgamma ) binds to and is activated by LPA and its analogs including fatty alcohol phosphates
Wu et al., Mol Cancer Res 2011
(Breast Neoplasms...) :
LPA stimulated p21 via LPA ( 1 ) and LPA ( 2 ) receptors and Erk dependent activation of the CCAAT/enhancer binding protein beta transcription factor independent of p53
Tsukahara et al., Scientific reports 2012
(Colonic Neoplasms) :
We encapsulated cPA in gelatin based hydrogels and examined its ability to inhibit the viability and migration of HT-29 and DLD-1 cells in vitro and the LPA induced activity of the transcription factor peroxisome proliferator activated receptor gamma ( PPAR? )