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TCF3 — TLR4

Text-mined interactions from Literome

Wietek et al., J Biol Chem 2003 : Interferon regulatory factor (IRF) 3 is a transcription factor that binds the interferon-sensitive response element ( ISRE ) and is activated by Toll-like receptor 3 (TLR3) and TLR4
Youn et al., Int Immunopharmacol 2008 : Selenium suppresses the activation of transcription factor NF-kappa B and IRF3 induced by TLR3 or TLR4 agonists
Scanzello et al., Curr Opin Rheumatol 2008 (Chronic Disease...) : TLRs are expressed and functional in the joint, and many proteases and cytokines that promote cartilage catabolism are dependent on nuclear factor-kappaB, a TLR activated transcription factor
Sun et al., Circ Res 2009 : TLR signaling via p38 led to phosphorylation and activation of the transcription factor Microphthalmia transcription factor, acting at E-box elements in the Ctsk promoter
Marsh et al., J Neurosci 2009 (Infarction, Middle Cerebral Artery...) : TLR4 can induce both IFNbeta and interferon stimulated genes through its adapter molecule Toll/interleukin receptor domain containing adaptor inducing IFNbeta ( TRIF ) and the IRF3 transcription factor
Hankins et al., J Biol Chem 2011 : TLR4 signaling ultimately leads to activation of the transcription factor , nuclear factor ?B ( NF-?B ), and the production of cytokines