Gene interactions and pathways from curated databases and text-mining

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MUC13 — TFAP2A

Text-mined interactions from Literome

Fauquette et al., Carcinogenesis 2007 (Pancreatic Neoplasms) : Transcription factor AP-2alpha represses both the mucin MUC4 expression and pancreatic cancer cell proliferation
Braeuer et al., Semin Cancer Biol 2011 (Melanoma...) : AP-2a regulates the expression of c-KIT, MMP-2, VEGF, and the adhesion molecule MCAM/MUC18
Bar-Eli et al., J Cell Physiol 1997 (Disease Progression...) : The expression of c-KIT and other genes associated with malignant melanoma ( such as MCAM/MUC18 ) is highly regulated by the transcription factor AP-2
Jean et al., J Biol Chem 1998 (Melanoma...) : These results indicate that the expression of MCAM/MUC18 is regulated by AP-2 and that enforced AP-2 expression suppresses tumorigenicity and metastatic potential of human melanoma cells, possibly by down regulating MCAM/MUC18 gene expression