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HDAC1 — TGFB1
Text-mined interactions from Literome
Izutsu et al., Blood 2001
(Cell Transformation, Neoplastic...) :
The corepressor
CtBP interacts with Evi-1 to
repress transforming growth factor beta signaling
Zhao et al., Cancer Res 2003
(Carcinoma, Pancreatic Ductal...) :
Requirement of a specific Sp1 site for
histone deacetylase mediated repression of
transforming growth factor beta Type II receptor expression in human pancreatic cancer cells ... In this study, we demonstrate a novel mechanism by which down-regulation of
transforming growth factor beta type II receptor ( TbetaRII ) is
mediated by a
histone deacetylase (HDAC) in pancreatic ductal adenocarcinoma ( PDAC ) cells
Young et al., FEBS J 2005
:
Differential
effects of
histone deacetylase inhibitors on phorbol ester- and
TGF-beta1 induced murine tissue inhibitor of metalloproteinases-1 gene expression
Li et al., Gastroenterology 2007
(Carcinoma, Hepatocellular...) :
The
histone deacetylase (HDAC) inhibitor Tricostatin A partially
blocked the
TGFbeta1 inhibition of CYP7A1 mRNA expression, whereas TGFbeta1 decreased histone 3 acetylation in the CYP7A1 chromatin
Lei et al., Int J Biochem Cell Biol 2010
:
Three structurally unrelated
HDAC inhibitors completely
suppress transforming growth factor-beta1 ( TGF-beta1 ) -induced EMT in AML-12 murine hepatocytes and primary mouse hepatocytes
Iavarone et al., Mol Cell Biol 1999
:
E2F and
histone deacetylase mediate
transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest