Gene interactions and pathways from curated databases and text-mining

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HDAC1 — TGFB1

Text-mined interactions from Literome

Izutsu et al., Blood 2001 (Cell Transformation, Neoplastic...) : The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling
Zhao et al., Cancer Res 2003 (Carcinoma, Pancreatic Ductal...) : Requirement of a specific Sp1 site for histone deacetylase mediated repression of transforming growth factor beta Type II receptor expression in human pancreatic cancer cells ... In this study, we demonstrate a novel mechanism by which down-regulation of transforming growth factor beta type II receptor ( TbetaRII ) is mediated by a histone deacetylase (HDAC) in pancreatic ductal adenocarcinoma ( PDAC ) cells
Young et al., FEBS J 2005 : Differential effects of histone deacetylase inhibitors on phorbol ester- and TGF-beta1 induced murine tissue inhibitor of metalloproteinases-1 gene expression
Li et al., Gastroenterology 2007 (Carcinoma, Hepatocellular...) : The histone deacetylase (HDAC) inhibitor Tricostatin A partially blocked the TGFbeta1 inhibition of CYP7A1 mRNA expression, whereas TGFbeta1 decreased histone 3 acetylation in the CYP7A1 chromatin
Lei et al., Int J Biochem Cell Biol 2010 : Three structurally unrelated HDAC inhibitors completely suppress transforming growth factor-beta1 ( TGF-beta1 ) -induced EMT in AML-12 murine hepatocytes and primary mouse hepatocytes
Iavarone et al., Mol Cell Biol 1999 : E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest