Gene interactions and pathways from curated databases and text-mining

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IGFBP1 — TGFB2

Text-mined interactions from Literome

Pereira et al., Am J Physiol Endocrinol Metab 2000 : Parathyroid hormone decreased, whereas transforming growth factor-beta and, to a lesser extent, bone morphogenetic protein 2 increased CTGF/IGFBP-rP2 mRNA levels, but other hormones and growth factors had no effect
Kuemmerle et al., Am J Physiol Gastrointest Liver Physiol 2004 : Two mechanisms for this effect have been identified : IGFBP-3 can directly activate transforming growth factor-beta ( TGF-beta ) receptors or it can undergo direct nuclear translocation