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E2F1 — TK2

Text-mined interactions from Literome

Ogris et al., J Virol 1993 : A binding site for transcription factor E2F is a target for trans activation of murine thymidine kinase by polyomavirus large T antigen and plays an important role in growth regulation of the gene
Hengstschläger et al., Oncogene 1996 (Precursor Cell Lymphoblastic Leukemia-Lymphoma) : The role of p16 in the E2F dependent thymidine kinase regulation ... Phosphorylation of the retinoblastoma protein by cyclin dependent kinases 4 and 6 prevents its interaction with the transcription factor E2F , which subsequently promotes the expression of S phase regulated genes, such as thymidine kinase