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TLR1 — TLR7
Text-mined interactions from Literome
Sel et al., J Immunol 2007
(Asthma...) :
These data indicate that TLR-3 or
TLR-7 activation by viral
TLR ligands has both preventive as well as suppressive effects on experimental asthma which is mediated by the additive effects of IL-12 and IL-10
Bayas et al., Clin Exp Immunol 2009
(Bacterial Infections...) :
In peripheral blood mononuclear cells,
TLR-9 stimulation with type A CpG ODN
resulted in a higher expression of
TLR-1 , -2, -4, -5 and -8 in MS patients ( n = 7 ) compared with healthy controls ( n = 11 )
Goethals et al., Glia 2010
(Wallerian Degeneration) :
Upon axotomy,
TLR1 becomes strongly
induced , while most other
TLR expression levels remain unaffected
Yang et al., Bing Du Xue Bao 2011
(Marek Disease...) :
By comparing the TLRs transcription between YL040920 and CVI988/Rispens infected microglia, it was suggested that vvMDV YL040920 might
induce more
TLR15 transcript than the attenuated vaccine strain CVI988/Rispens ( P < or = 0.01/0.001 ), while CVI988/Rispens induced more
TLR1LB transcript than YL040920 ( P < or = 0.001 )
Kwissa et al., Blood 2012
:
In the draining lymph nodes ( LNs ), consistent with the effects in blood, all
TLR-Ls induced expansion of CD14 ( + ) monocytes, but only
TLR7/8-L and TLR9-L expanded the activated CD14 ( + ) CD16 ( + ) cells
Römmler et al., J Immunol 2013
:
Whereas TLR9 induced TNF-a secretion of bone marrow derived macrophages and conventional dendritic cells was equally inhibited by INH-ODN 2088 and G-modified INH-ODNs such as INH-ODN 24888,
TLR7 induced TNF-a release and
TLR7- and TLR9 induced IL-12p40 release were significantly more impaired by G-modified INH-ODNs