Gene interactions and pathways from curated databases and text-mining

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TLR1 — TLR7

Text-mined interactions from Literome

Sel et al., J Immunol 2007 (Asthma...) : These data indicate that TLR-3 or TLR-7 activation by viral TLR ligands has both preventive as well as suppressive effects on experimental asthma which is mediated by the additive effects of IL-12 and IL-10
Bayas et al., Clin Exp Immunol 2009 (Bacterial Infections...) : In peripheral blood mononuclear cells, TLR-9 stimulation with type A CpG ODN resulted in a higher expression of TLR-1 , -2, -4, -5 and -8 in MS patients ( n = 7 ) compared with healthy controls ( n = 11 )
Goethals et al., Glia 2010 (Wallerian Degeneration) : Upon axotomy, TLR1 becomes strongly induced , while most other TLR expression levels remain unaffected
Yang et al., Bing Du Xue Bao 2011 (Marek Disease...) : By comparing the TLRs transcription between YL040920 and CVI988/Rispens infected microglia, it was suggested that vvMDV YL040920 might induce more TLR15 transcript than the attenuated vaccine strain CVI988/Rispens ( P < or = 0.01/0.001 ), while CVI988/Rispens induced more TLR1LB transcript than YL040920 ( P < or = 0.001 )
Kwissa et al., Blood 2012 : In the draining lymph nodes ( LNs ), consistent with the effects in blood, all TLR-Ls induced expansion of CD14 ( + ) monocytes, but only TLR7/8-L and TLR9-L expanded the activated CD14 ( + ) CD16 ( + ) cells
Römmler et al., J Immunol 2013 : Whereas TLR9 induced TNF-a secretion of bone marrow derived macrophages and conventional dendritic cells was equally inhibited by INH-ODN 2088 and G-modified INH-ODNs such as INH-ODN 24888, TLR7 induced TNF-a release and TLR7- and TLR9 induced IL-12p40 release were significantly more impaired by G-modified INH-ODNs