Gene interactions and pathways from curated databases and text-mining

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MMP13 — TNC

Text-mined interactions from Literome

Wallner et al., Arterioscler Thromb Vasc Biol 2004 : Together with our previous observations, our data suggest that Tn-C upregulates MMP expression that cleaves Tn-C into fragments containing the EGF-like domain
Hasaneen et al., FASEB J 2005 (Asthma) : Our results show that cyclic strain increased the proliferation and migration of HASM ; cyclic strain increased release and activation of MMP-1, -2, and -3 and membrane type 1-MMP ; MMP release was preceded by an increase in extracellular MMP inducer ; Prinomastat [ a MMP inhibitor ( MMPI ) ] significantly decreased cyclic strain induced proliferation and migration of HASM ; and the strain induced increase in the release of MMPs was accompanied by an increase in tenascin-C release