Gene interactions and pathways from curated databases and text-mining

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TNC — TNF

Text-mined interactions from Literome

Scherberich et al., Oncogene 2005 (Breast Neoplasms...) : TNF-alpha induced the expression of both tenascin-W and tenascin-C , and this induction was p38MAPK- and cyclooxygenase dependent
Nakoshi et al., J Rheumatol 2008 (Osteoarthritis) : Regulation of tenascin-C expression by tumor necrosis factor-alpha in cultured human osteoarthritis chondrocytes ... We investigated regulation of tenascin-C expression by TNF-alpha through nuclear factor-alphaB ( NF-kappaB ) in OA cartilage in vivo and in vitro ... TNF-alpha stimulated tenascin-C expression through NF-kappaB signaling with RelA activation in cultured OA chondrocytes, suggesting involvement of tenascin-C in OA cartilage remodeling
Meuronen et al., Respir Res 2011 (Airway Remodeling...) : The expression of tenascin-C in the lungs of OVA challenged STAT4-/- mice was weaker than in those of OVA challenged WT and STAT6-/- mice suggesting that TNF-a and IFN-? may regulate tenascin-C expression in vivo ... The stimulation of human fibroblasts with TNF-a and IFN-? induced the expression of tenascin-C confirming our in vivo findings