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NTRK1 — TNF
Text-mined interactions from Literome
Manni et al., Clin Exp Rheumatol 2003
(Inflammation...) :
NGF, but not IL-1 beta,
TNF-alpha and CCK-8,
enhances the expression of
TrkA in isolated synovial cells
Oda et al., J Pharmacol Exp Ther 2008
(Hemolysis) :
Furthermore, K252a, a
TrkA inhibitor, and PD98059 ( 2'-amino-3'-methoxyflavone ), an ERK1/2 inhibitor,
inhibited the toxin induced release of
TNF-alpha from neutrophils ... The observation shows that the toxin induced release of
TNF-alpha is
dependent on the activation of ERK/mitogen activated protein kinase signal transduction via
TrkA in neutrophils and that ERM specifically blocks the toxin induced events through the activation of neutrophils
Raychaudhuri et al., Scand J Rheumatol 2009
(Arthritis...) :
FACS studies showed that unstimulated FLS expressed low levels of NGF and the high-affinity NGF-tyrosine kinase receptor TrkA, and
TNFalpha and IL-1beta
increased NGF and
TrkA expression in FLS
Oda et al., Nihon rinsho. Japanese journal of clinical medicine 2012
(Gas Gangrene...) :
The toxin induced release of
TNF-alpha from neutrophils and macrophages is
dependent on the activation of ERK1/2 signal transduction via
TrkA receptor