Gene interactions and pathways from curated databases and text-mining

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SOAT1 — TNF

Text-mined interactions from Literome

Tliba et al., J Biol Chem 2003 (Inflammation) : In this study, TNFalpha in a time dependent manner activated both janus tyrosine kinase 1 and Tyk2 tyrosine kinase and increased the nuclear translocation of interferon-regulatory factor-1, STAT1 , and STAT2 in human airway smooth muscle cells
Hermoso et al., Mol Cell Biol 2004 : Molecular studies show that the IkappaBalpha superrepressor or a STAT dominant negative element prevented TNF-alpha and dexamethasone stimulation of TLR2 promoter
Wu et al., Kidney Int 2005 : Stimulation of mesangial cells with TNF-alpha resulted in enhanced DNA binding activity of STAT ( 3 )
Liu et al., J Immunol 2007 : Activation of NF-kappaB, STAT6 , and STAT1 was induced in eosinophils by TNF-alpha , IL-4, and IFN-gamma, respectively
Rosengren et al., Ann Rheum Dis 2012 (Arthritis, Rheumatoid) : Unexpectedly, although tumour necrosis factor (TNF) did not induce immediate phosphorylation of either STAT , CP-690,550 inhibited TNF induced expression of several chemokines ( IP-10, RANTES and MCP1 ) at the messenger RNA and protein levels
Guo et al., J Immunol 1998 : Induction of Jak/STAT signaling by activation of the type 1 TNF receptor