Gene interactions and pathways from curated databases and text-mining

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RAD51 — TOP1

Text-mined interactions from Literome

Reckinger et al., Nucleic Acids Res 2007 : RecA can stimulate the relaxation activity of topoisomerase I : Molecular basis of topoisomerase mediated genome-wide transcriptional responses in Escherichia coli ... RecA has no effect on the supercoiling activity of gyrase but stimulates the relaxation activity of topoisomerase I
Hartsuiker et al., Mol Cell 2009 : Distinct requirements for the Rad32 ( Mre11 ) nuclease and Ctp1 ( CtIP ) in the removal of covalently bound topoisomerase I and II from DNA
Liu et al., J Antimicrob Chemother 2011 : To explore the role of topoisomerase I in gene activation and increased RecA levels during the bacterial SOS response, as well as the effect of antibiotic treatment and stress challenge on cell killing initiated by trapped topoisomerase I cleavage complex